Complaint
Tretinoin, can be called as Tretinoin Vitamin A Acid, Trans Vitamin A Acid either, is the metabolic intermediate of the Vitamin A in our internal system. It is a kind of raw material used in pharmaceutical area.
Function:
1. It is a drug commonly used to treat acne vulgaris and keratosis pilaris.
2. It is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
3. It can stimulate skin growth and keep epidermic normal.
4. It can slow down skin aging process for solarization, remove tiny wrinkles.
5. It can reduce skin roughness, so skin will become ruddy.
Application:
1. Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
2. Tretinoin can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3. Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.
Specification
| Specification | ||
| Item | Specification | Result |
| Appearance | Yellow Crystalline Powder | Complies |
| Related substance (HPLC) | Total impurity ≤0.5% | 0.20% |
| Max single impurity ≤0.1% | 0.06% | |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.80% |
| Sieve analysis | 100% pass 80 mesh | Complies |
| Loss on Drying | ≤1.0% | 0.12% |
| Residue on Ignition | ≤1.0% | 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
| Residual Pesticide | Negative | Complies |
| Microbiology | ||
| Total Plate Count | <1000cfu/g | Complies |
| Yeast & Mold | <100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
