Description
Paracetamol
The international non-proprietary drug name is paracetamol.It is the most commonly used non-anti-inflammatory antipyretic analgesic,The antipyretic effect is similar to that of aspirin,The analgesic effect is weak,No anti - inflammatory anti - rheumatism effect,It is the best kind of the acetanilides.It is especially suitable for patients who cannot use carboxylic acid drugs.Used for cold, toothache, etc.Acetaminophen is also an intermediate in organic synthesis,the stabilizer of hydrogen peroxide, photographic chemical. Product Name | Acetaminophen Powder Paracetamol API |
Appearance | White or almost white powder |
CAS No. | 103-90-2 |
MF | C8H9NO2 |
Molecular Weight | 151.16 g/mol |
EINECS No | 203-157-5 |
Storage | Keep in a cool, dry, dark location |
Shelf Life | 24 Months |
SpecificationAppearance | White or almost white ,crystalline powder. |
Identification | A:IR absorption | Complies |
B:UV absorption | Complies |
C:TLC | Complies |
Melting point | 168~172°C |
Water | Not more than0.5% |
Related substance | Impurity(chloroacetanilide)not more than 10 ppm |
Impurity K(4-aminophenol)not more than 50 ppm |
Impurity F(4-nitrophenol)not more than 0.05% |
any other impurity not more than 0.05% |
Total of other impurities not more than 0.1% |
Residue on ignition | Not more than 0.1% |
Chloride | Not more than 0.014% |
Sulfate | Not more than 0.02% |
Sulfide | Conforms |
Heavy metals | Not more than 0.001% |
Free p-aminophenol | Not more than 0.005% |
Limit of P-chloroacetanilide | Not more than 0.001% |
Readily carbonizable substances | Conforms |
Residual solvents | Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% |
Assay(anhydrous basis) | 99.0~101.0% |
Conclusion: Complies with USP34/ BP2011 |
Application&Function
1. Paracetamol is approved for reducing fever in people of all ages.
2. Paracetamol is used for the relief of pains associated with many parts of the body.
3. Paracetamol has analgesic properties comparable to those of aspirin,while its anti-inflammatory effects are weaker.
4. Paracetamol is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern.5. Paracetamol powder nutritional supplemen mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics.Serine constitute the human body of several kinds of essential amino acid of protein a,for the construction of protein has a very important role.