High quality/High cost performance of Ketoprofen for Injection with GMP

Min.Order: 1,000,000
Product origin: Zibo, Shandong, China
Infringement complaint: complaintComplaint
US$ 0.01

Description
Product name: KETOPROFEN for injection
Specification: 100 mg
Certification: GMP, ISO9001, ISO14001
Shife life: 36 months
Standard: ES 
 


Molecular formula: C16H14O3

Formula weight: 254.29

Chemical name: Alpha - methyl -3- benzoyl - phenylacetic acid. 

Pharmacokinetics: Easy to absorb by mouth. Absorption slows down when taken with food and milk, but the absorption is still relatively complete. The blood concentration of the drug reached the peak value about 1~2 hours after the first dose, and reached the stable state in less than 1 day. Plasma protein binding rate is 99%(lower in the elderly). The half-life (t1/2) is 1.6~4 hours (mean 3 hours), 60% of which is excreted in urine within 24 hours, mainly in the form of glucuronic acid conjugates, and up to 10% in the original form. The clearance rate of elderly patients with liver and kidney dysfunction decreased by 22%~50%. 

[indications]
Used for joint swelling and pain caused by arthritis, ankylosing spondylitis, dysmenorrhea, 
Toothache, postoperative pain and cancer pain. 
[dverse reaction]
Gastrointestinal reactions are common, such as stomach pain or discomfort, bloating, nausea, vomiting, loss of appetite, diarrhea, constipation, etc. In severe cases, upper gastrointestinal ulcer, bleeding and perforation may occur. 2. Allergic reactions: Allergic dermatitis, pruritus, exfoliative dermatitis, laryngeal edema, bronchospasm (irritability), etc. 3. Eyes: Blurred vision, retinal hemorrhage. Cardiovascular system: Arrhythmia, elevated blood pressure, palpitations. 5. Central nervous system: Dizziness, headache, tinnitus, hearing loss, mental tension, mental depression, hallucinations, lethargy, numbness of limbs, etc. 6. Liver and kidney: Liver damage, renal function decline, interstitial nephritis, nephropathy. Blood system: Epistaxis, granulocytopenia, thrombocytopenia, hemolytic anemia. 8. Others: Water retention (rapid weight gain, decreased urine volume, facial edema, etc. ), stomatitis, hyperhidrosis, etc. 

[storage] shading, sealed storage. 

[production enterprise] REYOUNG pharmaceutical Co., Ltd







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