Complaint
Product Description
Beta-tricalcium phosphate(β-TCP)
β-tricalcium phosphate (β-TCP) having a good biodegradability, biocompatibility, and ability to induce bone, implant body, down the degradation of calcium, phosphorus can enter the circulatory system in vivo, the formation of new bone, so the application of a large number of the bone tissue repair. But its poor toughness, brittle, poor load bearing. Poly-L-lactic acid (PLLA) because of their good biocompatibility and biodegradability advantages, also used in bone tissue repair.
Chemical name: tricalcium phosphate; Alias: Calcium
Molecular Weight: 310.18
Formula: Ca3 (PO4) 2
Molecular Structure:
CAS No.: 7758-87-4
Density: 3.14 g/cm3
Melting point: 1670 ºC
Refractive index: 1.626
Characteristics: β-TCP component , similar to the composition and bone mineral, is a white amorphous powder, odorless. Stable in air, water decomposition, can be dissolved in dilute hydrochloric acid and nitric acid, almost insoluble in water, ethanol and acetic acid. Biological compatibility, the degradation can occur under physiological conditions, is tissue absorption.
Specifications: Meet People pharmaceutical industry standards YY / T 0683-2008 "surgical implants β-tricalcium phosphate" requirement.
Product Analysis
Items | Specifications |
Appearance | White powder |
Density | 3.14 g/cm3 |
Melting point | 1670 ºC |
Formula | Ca3 (PO4) 2 |
Refractive index | 1.626 |
Molecular Weight | 310.18 |
Average particle size | 0.5-15um |
Purity | 96% |
Function and Application
Major medical purposes:
Tricalcium phosphate has good biocompatibility, bioactivity and biodegradability, is ideal for human hard tissue repair and replacement materials in the biomedical engineering field has been closely watched by the people. A commonly used medical tricalcium phosphate form of a special-β-tricalcium phosphate. Good biocompatibility, bioactivity and biodegradability, is ideal for human hard tissue repair and replacement materials as artificial bone materials, has been widely used in orthopedics, plastic and cosmetic surgery, dental, rehabilitation due to trauma, cancer, inflammation, bone disease and other bone defects and bone due to fusion. Can be used as a safe food nutrition fortifier added to enhance calcium intake, can also be used for the prevention or treatment of calcium deficiency symptoms. Also serves as an anti-caking agent in foods, PH value regulating agents, buffers, etc.
β-tricalcium phosphate is mainly calcium, phosphorus, whose composition and similar to the inorganic component of bone matrix, with good bone. Animal or human cells in the β-tricalcium phosphate material, normal growth, differentiation and reproduction. Through a large number of experimental studies have shown that: β-tricalcium phosphate bone marrow hematopoietic function without adverse reaction, no rejection, no acute toxicity, will not cancerous, no allergies. Therefore, β-tricalcium phosphate is widely used in joints and spinal fusion, limb trauma, oral maxillofacial surgery, cardiovascular surgery, periodontal and filling voids and so on. As people of β-tricalcium phosphate deepening of the research, its application also appeared in the form of diversification, and in clinical medicine reflects better performance.
The degree of hemolysis <5%, when the β-tricalcium phosphate to be implanted in the human body after body fluids can degrade and absorption of calcium and phosphorus to be absorbed into the body fluid circulation system, implanted in the body after a certain time the β-phosphate tricalcium gradually dissolved away, the formation of new bone. β-tricalcium phosphate combined with autologous bone marrow is an ideal method for treatment of bone defects after implantation no significant local tissue inflammation and other reactions, as a carrier of anti-TB drugs and antibiotics, osteomyelitis stuffer to the affected area, the basic repair of bone defects.
