Cobalamin interacts with folic acid in several interesting ways:
Product Name | Vitamin B12 | Batch No | 201811003 |
Labelled assay | 98% | Quantity | 5.7kg |
Manufacturing Date | 2018-11-03 | Expiry Date | 2023-10-31 |
Analysis Date | 2018-11-08 | Report Date | 2018-11-08 |
Test Method | Ph.Eur.9.0 BP2017 and in house standard |
Item | Standards | Results | Test Methods |
Appearance | Dark red crystal or dark red crystalline | Qualified | Monograph: 057 Visual method |
Identification A | UV: Absorption maxing at361±1nm, 550±2nm. | Qualified | Ph. Eur. Monograph/Ph. Eur<2.2.25> |
A361nm/A278nm; 1.70-1.90 | 1.87 | ||
A361NM/A550nm; 3.15-3.40 | 3.27 | ||
Identification B | TLC: The principal spot in the chromatogram obtained with the test solution is similar in position, color and size to the principal spot in the chromatogram obtained with the reference solution. | Qualified | Ph. Eur. Monograph/Ph. Eur<2.2.27> |
Assay | 96.0%-102.0% | 98.4% | Ph. Eur. Monograph |
Loss On Drying | ≤12.0% | 2.0% | Ph. Eur. Monograph/Ph. Eur<2.2.32> |
Related substances | Total impurities≤3.0% | 2.4% | Ph. Eur. Monograph/ Ph. Eur<2.2.29>(HPLC) |
Residual solvents | Acetone≤5000ppm | No found | In house/(GC) |