Function 1. Used in common food It can be added to foods such as dairy products, cereals and their products, liquids and milk beverages, salt, biscuits, scented tea, infant formula powder and other foods to make nutritional fortified foods. 2. Used in health food In 2002, the US FDA first approved PharmaSe, Inc. In our country, at least it can be used as a raw material to develop the following health foods with various functions. (1) As a nutrient supplement: supplement the trace element . (2) Enhance immunity A large number of studies have shown that the effects
Application 1. L-Selenium-methylselenocysteine compared to inorganicselenium:
Inorganic selenide (selenite) is mainly characterized by cytotoxicity (such as cell detachment, increased intracellular vacuoles,cell membrane rupture, cell necrosis and acute lysis) at low concentrations, accompanied by decreased DNA synthesis and resistance. The cell cycle is in the S/G2-M phase. In addition, it can cause DNA damage and cell death, which can cause DNA single-strand breaks within a few hours of action. The form of cell death is mainly necrosis or acute dissolution, while the action of organic selenium compounds such as p-XSC, methyl selenate, selenomethionine and L-selenium-methyl selenocysteine is different. At high concentrations, there is little change in cell morphology, which has an inhibitory effect on cell growth but is mild, and generally does not cause DNA breakage.
2. L-Selenium-methylselenocysteine compared with other organic selenium:
It has the advantages of clear structure, stable content and clear metabolic mechanism in the human body. Selenium-rich yeast, selenoprotein, selenium-enriched edible fungus powder and other products in selenium content is not fixed, because the effective supplemental dose of selenium is close to the poisoning measurement, so in addition to non-toxic selenium carrageenan, selenium-enriched yeast\ There is a certain risk in the food safety of selenoprotein and selenium-enriched edible fungi.
3. L-Selenium-methylselenocysteine compared to L-selenomethionine:
L-Selenium-methylselenocysteine and L-selenomethionine are the only two selenium-containing amino acids in nature, and are also known as the third-generation selenium-enriched varieties.
Studies have shown that L-selenium-methylselenocysteine is directly converted to methyl selenide by degradation of β-degrading enzyme, unlike L-selenomethionine which cannot be non-specifically incorporated. Since methionine-tRNA cannot distinguish between methionine and L-selenomethionine, when methionine intake is limited, a large proportion of L-selenomethionine instead of methionine is non-specifically incorporated into animal proteins. Compared with other forms of selenium, if L-selenomethionine is used as the main source of selenium in animal foods, selenium will accumulate in tissues and easily cause selenium poisoning. Therefore, L-selenium-methyl selenide Cystine has higher food safety than L-selenomethionine..