Complaint
L-Dopa (Levodopa) is a prodrug of dopamine (DA), which itself has no pharmacological activity. It enters the central nervous system through the blood-brain barrier, and is transformed into DA by dopa decarboxylase to exert pharmacological effects.
Pharmacological effects: It is an anti-parkinsonian drug. It enters the brain tissue through the blood-brain barrier, and is decarboxylated by dopa decarboxylase to be converted into dopamine to play a role. For primary parkinsonism and non-pharmaceutical parkinsonia syndrome, the effect is better for moderate and mild cases.
| Product Name: | Levodopa |
| Synonyms: | 2-amino-3-(3,4-dihydroxyphenyl)propanoicacid;3,4-Dihydroxyphenylalanine(form2);3,4-Dihydroxyphenyl-L-alanine;3,4-DIHYDROXY-L-PHENYLALANINE;3,4-L-DIHYDROXYPHENYLALANINE;3-(3,4-DIHYDROXYPHENYL)-L-ALANINE;3-HYDROXY-L-TYROSINE;BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE |
| CAS: | 59-92-7 |
| MF: | C9H11NO4 |
| MW: | 197.19 |
| EINECS: | 200-445-2 |
| Product Categories: | Inhibitors;plant extract;Amino Acids;Biochemistry;Biological-modified Amino Acids;Dopamine receptor;Pharmaceutical;Nutritional Supplements;Natural Plant Extract;Amino Acids & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Plant extracts;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;LARADOPA |
| Mol File: | 59-92-7.mol |
Testing Items | Specifications | Results |
Appearance | White to off-white, odorless crystalline powder | Off-white, odorless crystalline powder |
Identification IR | Conforms to reference spectrum | Conforms |
HPLC | Conforms to the chromatogram of the standard preparation. | Conforms |
Related compound A (%) | NMT 0.1 | Undetected |
L-Tyrosine (%) | NMT 0.1 | Undetected |
Related compound B (%) | NMT 0.5 | 0.02 |
L-Veratrylglycine(%) | NMT 0.1 | Undetected |
Individual unknown Impurity (%) | NMT 0.1 | 0.02 |
Total Impurity (%) | NMT 1.1 | 0.09 |
Heavy metal (%) | NMT 0.002 | <0.001 |
Loss on drying (%) | NMT 0.5 | 0.12 |
Residue on ignition (%) | NMT 0.1 | 0.04 |
Assay (on dried basis) (%) | 98.0~102.0 | 99.6 |
Specific rotation(°) | -160~-167 | -162 |
Residual Solvents: LOD (%) | NMT 0.5 | 0.12 |
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