Veterinary Medicine 99% CAS 57-66-9 Probenecid Powder

Min.Order: 25

Product origin: Hefei, Anhui, China

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US$ 35 ~ 70

Description

CAS 57-66-9 Probenecid

Product name: Probenecid

Other name: Benemid

Appearance: White crystalline powder

CAS NO.: 57-66-9

M.F.: C13H19NO4S

M.W.: 285.359

Grade: Pharmaceutical grade

Probenecid inhibits the active reabsorption of urate in the proximal tubules, increases the excretion of urate and reduces the concentration of urate in the blood. It can alleviate or prevent the formation of urate nodules, reduce joint damage, and promote the dissolution of formed urate. No anti-inflammatory and analgesic effects. It can competitively inhibit the secretion of weak organic acids (such as penicillin and cephalosporins) in the renal tubules, so it can increase the blood concentration of these antibiotics and prolong their action time.

Function
Probenecid in the treatment of hyperuricemia with chronic gouty arthritis and tophi, but the glomerular filtration must be greater than 50-60 ml/min; no history of kidney stones or kidney stones; non-acidic urine; no salicylic acid Drugs.
Probenecid, as an adjuvant drug for antibiotic therapy, can improve the efficacy of antibiotics.
Probenecid should not be combined with salicylic acid, aspirin, etanic acid, hydrochlorothiazide, phenylbutazone, indomethacin, naproxen, allopurinol, sulfa drugs, methotrexate and oral hypoglycemic drugs The drugs are taken as equivalent, because this product can inhibit the renal tubular excretion of these drugs, so that their effects and toxicity are increased.

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