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Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1

Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1

Min.Order: 1
Product origin: Shenzhen, Guangdong, China
Infringement complaint: complaintComplaint
US$ 1

Description
Supply Top Quality Antipyretic Analgesic Drugs Indometacin Powder CAS 53-86-1

Product Name: Indometacin
Synonyms: 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin meth-anol solution;indomethacin usp;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
EINECS: 200-186-5
Appearance: White to off-white powder

Product Name:  Indometacin  
Batch No.CH221121Quantity8.5kgs
ItemsStandardsResults
AppearanceWhite or off-white solid powderComplies
IdentificationBy IRComplies
By HPLCComplies
SolubilitySoluble in DMF, sparingly soluble in THF, slightly soluble in meth-anol and acet-onitrile, very sightly soluble in ethanol and dichloro-methane, insoluble in waterComplies
Polymorphic FormPolymorphic form 1Complies
Melting Point211ºC~216ºC212.8ºC~214.9ºC
Water Content≤ 0.50%0.10%
Heavy Metals≤ 20ppmComplies
Residue on Ignition≤ 0.20%0.09%
Related SubstanceAny single impurity: ≤0.10%0.06%
Total Impurities: ≤1.00%0.16%
Assay                 (on the anhydrous basis)98.0%~102.0%99.94%
Particle SizeD90: ≤100µmComplies
Reference StandardIn-house Standard
ConclusionThe product complied to In-house standard.
StoragePreserve in tight,light-resistant containers in a cool place


Uses:
1.Anti-rheumatism: adult dosage: oral: early quantity from 25 to 50 mg each time, 2~4 times a day, immediately take at food service or after a meal. Such as good tolerance, the daily dosage can be increased from 25 to 50 mg per week, the most mount should not be more than 200 mg a day. Arthritis patients such as persistent pain at night or morning stiffness, can give quantity of 100 mg in bed all day.
2. Resistance to gout: oral: At the beginning quantity is 100 mg once, then 50 mg, three times a day, until the pain relief, and then gradually reduced as soon as possible, until the drug withdrawal.
3. Antifebrile: adult dosage: oral: 25~50 mg each time, 3~4 times daily.Rectal drug delivery: every time 50 mg, 50 to 100 mg per day. Pediatric dosage: oral: 0.5~1 mg/kg each time, 3 times a day.

Indomethacin is a kind of stronger corticoid anti-inflammatory and antipyretic and analgesic, by inhibiting cyclooxygenase reducing the synthesis of prostaglandin (PG), to prevent the formation of the nere impulses, inflammation tissue inhibiting inflammatory reaction, including inhibition of leukocyte chemotaxis and lysosomal enzyme release, etc., and produce antipyretic, analgesic and anti-inflammatory effects. Indomethacin anti-inflammatory, antipyretic effect is very strong, its anti-inflammatory effect is better than bute, 84 times better than hydrocor-tisone, and sugar cortical hormone, used in combination with aspirin, bute, can reduce their dosage, toxic and side effects, improve curative effect; Second is antipyretic effect, 10 times than amidopyrine ;its analgesic action is weak , only to the inflammatory pain has obvious analgesic effect, but the effect is good for inflammatory pain than Baotai loose, analgin and salicylic acid. Clinical is mainly used for the salicylic acid, drugs are less tolerance or curative effect is not obvious in the acute and chronic rheumatic or rheumatoid arthritis, ankylosing spondylitis, slippery bursa phlogistic, tenosynovitis, articular capsulitis, osteoarthritis and acute gout and cancerous pain, etc.In recent years, the researchers try to use indomethacin biliary colic, dysmenorrhea, migraine, glomerulonephritis, polyuria, salmonella gastroenteritis, orthostatic hypotension, bart syndrome and so on, all have good curative effect.It can also be used to treat eye pigment meningitis, keratitis, scleritis, glaucoma and fever caused by cancer or other difficult to control the fever. Dermatologist for lupus erythematosus (sle), white plug syndrome, scleroderma, nodular erythema, herpes zoster, joint type of psoriasis, etc. photosensitive dermatitis induced by topical treatment of eczema, allergic dermatitis, and local pain.

Why Choose Us?
1.OEM/ODM Available.
2. Raw materials from chinese origin
3. Best quality in your requirement
4. Competitive price in china market
5 Fast delivery and free sample for your evaluation.Stock availability
6.Door to door shipping service is available.
7. Professional documents for your custom clearance.
8. Full experience of large numberscontainers loading in chinese sea port
9. Packing with pallet or as buyer's special request
10. Best after-service after shipment

Shenzhen Changhua Biotechnology Co., Ltd. A leading supplier of fine chemical in China, is located in Shenzhen. The unique geographical conditions of Shenzhen are favorable for transportation.

The company invests large fund and brains to R&D department to research fine chemical, biochemical, pharmaceutical & its intermediates products that fit the demand of the market. High level research group, advanced apparatus and good scientific atmosphere ensure the quality.

According to the GMP standard, the company has built 10000 m2 plant with the advanced equipment. The factory has a complete Q. A. & Q. C. System. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of SGS to be as audited supplier. We have the authority of export and import. Our products are sold both in the domestic and international market and highly recommended by our clients. In order to develop the market further, we are eager to cooperate with the manufactory and trading company around the globe to make a prosperous future.





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