Complaint
| TOLFENPYRAD Basic information |
| Description References |
| Product Name: | TOLFENPYRAD |
| CAS: | 129558-76-5 |
| MF: | C21H22ClN3O2 |
| MW: | 383.87 |
| Product Categories: | Agro-Products;Amines;Aromatics;Heterocycles;Pharmaceutical intermediates |
| Mol File: | 129558-76-5.mol |
| TOLFENPYRAD Chemical Properties |
| Melting point | 87~89ºC |
| Boiling point | 540.0±50.0 °C(Predicted) |
| density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | 0-6°C |
| form | neat |
| pka | 13.11±0.46(Predicted) |
| BRN | 13666608 |
| InChIKey | WPALTCMYPARVNV-UHFFFAOYSA-N |
| CAS DataBase Reference | 129558-76-5 |
| EPA Substance Registry System | 1H-Pyrazole-5-carboxamide, 4-chloro-3-ethyl-1-methyl-N-[[4-(4-ethylphenoxy)phenyl]methyl]- (129558-76-5) |
| Safety Information |
| Hazard Codes | Xn,N |
| Risk Statements | 20/22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| MSDS Information |
| TOLFENPYRAD Usage And Synthesis |
| Description | Tolfenpyrad is a pyrazole insecticide developed by Mitsubishi Chemical. It was first approved in 2002 in Japan under the trade name of Hachi-hachi. It has broad insecticidal activity against a variety of pests such as Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera and Acarina. It is especially effective against pests that are resistant to existing insecticides such as organophosphates and carbametes, because it supposedly possesses a new mode of action: inhibition of Complex I in the respiratory electron-transfer chain of mitochondria. It is applied for vegetables particularly cruciferous leafy varieties, cucurbits, cole crops, tea, fruits & nuts, selected row crops, and indoor ornamentals except cut flowers. |
| References | [1] http://sitem.herts.ac.uk/aeru/iupac/Reports/1687.htm [2] Koji Yamaguchi, Wakako Hikiji, Masahiko Takino, Kanju Saka, Makiko Hayashida, Tatsushige Fukunaga, Youkichi Ohno (2012) Analysis of Tolfenpyrad and its Metabolites in Plasma in a Tolfenpyrad Poisoning Case, 36, 529-537 |
| Uses | Tolfenpyrad |
