Humanin (HN) is a polypeptide and a naturally occurring micro-peptide which suppresses neuronal cell death induced by various Alzheimer's disease genes as studies showed. The Humanin peptide is encoded in the mitochondrial DNA[i] and functions as a cytoprotective protein, protecting cells from apoptosis. Apoptosis is programmed cell death. By protecting the cells from this lethal process, it keeps the cells healthy and protects neurons, muscle cells, cardiac tissue, and the retina of the eye as tests showed.
Research shows that humanin treatment can improve cardiovascular disease and Alzheimer's disease. With more extensive research, it could soon become an available over-the-counter medication for such health conditions.
What is Humanin Peptide?
Humanin is a micro-peptide, which means it is produced by short, open reading frames and does not undergo modification once produced. According to studies, this type of peptide ranges in size from 100-150 amino acids in length.
At only 24 amino acids in length, Humanin is actually one of the smallest micropeptides available. Its main feature is its interaction with the Bax protein to regulate apoptosis, eliminating the function of it when needed to preserve cells.
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