Complaint
Sodium Hyaluronate is the sodium salt of hyaluronic acid (HA), also known as hyaluronan, a glycosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units. HA is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. HA is a naturally occurring biopolymer involved in numerous biological processes including tissue hydration and structural scaffolding. HA is increasingly used as a reagent and investigated in medical, pharmaceutical and bioengineering applications. Its use as a reagent includes hydrogels for use in aesthetics, ophthalmology, rheumatology, urology, wound healing, and 3D bioprinting.
| Item | Specification | Result |
| Physical & Chemical Test | ||
| Appearance | White or almost white powder or granules | Complies |
| Infrared absorption | Positive | Complies |
| Reaction of sodium | Positive | Complies |
| Absorbance | ≤0.25 | 0.08 |
| Transparency | ≥99.0% | 100.0% |
| PH | 6.0~7.5 | 6.5 |
| Intrinsic viscosity | ≥22.40 dL/g | 22.66 dL/g |
| Molecular weight | ≥1.40×106 Da | 1.42×106 Da |
| Kinematic viscosity | Actual value | 52.57 mm²/s |
| Purity Test | ||
| Loss on drying | ≤10% | 9.34% |
| Residue on ignition | ≤20% | 18.85% |
| Heavy metals | ≤20ppm | <20ppm |
| Arsenic | ≤2ppm | <2ppm |
| Protein | ≤0.1% | 0.03% |
| Assay | 95.0%~105.0% | 96.6% |
| Glucuronic acid | 46.0%~51.0% | 46.7% |
| Microbiological Purity | ||
| Total bacterial count | ≤100CFU/g | <10CFU/g |
| Yeasts & mold | ≤20CFU/g | <10CFU/g |
| E.coli | Negative | Negative |
| Staph | Negative | Negative |
| Pseudomonas aeruginosa | Negative | Negative |
| Conclusion: This product complies with the standard of QB/T 4416-2012. | ||
Sodium hyaluronate is usually used for anti-aging and moisturizing because of its ability to improve firmness levels, smooth out fine lines, and hydrate the skin. You can find sodium hyaluronate in many products, including serums and moisturizers. It is also possible to take it as an oral supplement.
