What is Hydrogen? Hydrogen is the smallest molecule known in nature. Hydrogen has fast movement speed and strong penetration. After entering the human body, it is very easy to reach all parts of the body and the inside of tissues and cells. For example, hydrogen can reach the mitochondria and other fine structures in the cells, fundamentally adjusting the state of cells. Hydrogen has a protective effect on diabetes mellitus, arteriosclerosis, arthritis, sepsis and side effects of tumor chemoradiotherapy. It has a therapeutic effect on metabolic syndrome, dyslipidemia, type 2 diabetes mellitus, rheumatoid arthritis, decreased quality of life after cancer radiotherapy, side effects caused by uremic dialysis, and fatigue after exercise. And is the only known antioxidant that has a selective effect on free radicals.
Work principle Biological effects of H2.H2 exhibiting selective antioxidant and anti-inflammatory activities and modulating ER stress,mitochondria, and immune function. H2 selectively scavenged OH and ONOO-, up-regulated NRF-2 and HO-1, and down-regulated the expressions of proinflammatory and inflammatory cytokines TNF-A, NF-KB, INF-Y, Fas, FasL, IL-1A, IL-1β, IL-6, IL-8 and IL10.Down-regulated expression of endoplasmic reticulum stress-related factors GRP78 and TRAF2. H2 also reduces Mir-210 and activates OXPHOS in mitochondria. H2 increased CD4+CD25+Foxp3+Treg cells and maintained Thl/Th2 balance.
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