Complaint
Puya Supply Colestyramin Resin CAS 11041-12-6 For Reduce Blood Lipids
Product Name: CHOLESTYRAMINE RESIN
Synonyms: cholestyraminechloride;colestyramin;cuemid;polystyrenebenzyltrimethylaminoniumchloride;quantalan;DOWEX 1 X 2 CL-FORM;CHOLESTYRAMINE;CHOLESTYRAMINE RESIN
CAS: 11041-12-6
MF: C27H47N
MW: 385.66878
EINECS: 234-270-8
Product Categories: gel
Mol File: 11041-12-6.mol
Cholestyramine, is a strongly basic quaternary ammonium anion exchange resin, it is used in low-density lipoprotein hyperlipidemia that includesiia, IIb hyperlipidemia,it is the strongest cholesterol-lowering drug . After oral administration , it is not absorbed ,in the intestine the containing chlorin e ion is exchanged with the bile acid,it can bind stably with bile acids until the feces, it can reduce the absorption of exogenous cholesterol, hinder the enterohepatic circulation of bile acids absorbed into blood ,it can reduce the amount of bile acids in the blood , which prompt blood cholesterol conversion to bile acids, which lowers cholesterol. Cholestyramine has no lowering effect on triglycerides. Because of the powerful cholesterol-lowering effect, the product becomes the choice of drug for type IIa hyperlipoproteinemia. It shall be used in combination with drugs which can reduce blood triglyceride such as clofibrate or nicotinic acid for the treatment of type IIb hyperlipoproteinemia .For hyperlipoproteinemia III, IV, V , we should not use cholestyramine. In addition, the product can also be used for the treatment of skin itching caused by atherosclerosis and cirrhosis, cholelithiasis .
Colestyramin Resin CAS 11041-12-6 of Chemical Properties
solubility Insoluble in water, in methylene chlori de and in ethanol (96 per cent).
form neat
EPA Substance Registry System Cholestyramine (11041-12-6)
Function and Application of Colestyramin Resin CAS 11041-12-6
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