Piperine is a broad-spectrum anticonvulsant with the chemical formula C17H19NO3. Colorless monoclinic prism crystals, odorless, with burning sensation after taste. Neutral to litmus reagent. Soluble in chloroform, ethanol, ether, soluble in benzene and acetic acid, almost insoluble in water and petroleum ether. It can be extracted from the dried near-ripe or ripe fruit of pepper, a plant in the family Piperaceae. It has a good antagonism effect on experimental electric convulsions in mice, and is effective against convulsions and audiogenic seizures caused by pentylenetetrazol, picrotoxin and intraventricular injection tubes of curine and glutamic acid. There are varying degrees of resistance. It is also effective for certain types of epilepsy. Piperine is more toxic to flies than pyrethrum.
1.treatment for arthritis, rheumatism and skin disease or wound healing; 2.losing weight, its ability to increase in the metabolic rate of the body; 3.clearing heat and diuretic, expectorant, sedative and analgestic; 4.treating acute conjunctivitis, bronchitis, gastritis, enteritis and urinary stones; 5.enhancing immunity and supporting the intestinal absorption of nutrients.
1.Applied in the pharmaceutical field as the main anticonvulsant ingredient in Chinese prescriptions for the treatment of epilepsy 2.Applied in the food industry, as a spicy raw material, with bactericidal effect, such as used in brandy additives to give a spicy taste.
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