Complaint
Marya China pharma contrast medium vial liquid filling sealing production line with chemical research
Main Composition
The vial liquid filling line is composed of ultrasonic bottle washing machine, dryer sterilizer, vial filling stoppering machine, and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.
Performance Features
Technical Parameter
| Applicable Specification | 1ml-100ml vial (as per user's requirement) |
| Production Capacity | 1000-36000BPH |
| Number of Filling Head | 1-20, to be selected according to the output |
| Filling Accuracy | ≤ ±1% (according to drug characteristics) |
| Capping Qualified Rate | ≥99.9% |
| Filling Pumps | glass pump, metal pump, peristaltic pump, ceramic pump |
| Model | KGF4 | KGF6 | KGF8 | KGF10 | KGF12 | KGF20 |
| Applicable specifications | 2~30ml vial bottles | |||||
| Filling heads | 4 | 6 | 8 | 10 | 12 | 20 |
| Production capacity | 50-100bts/min | 80-150bts/min | 100-200bts/min | 150-300bts/min | 200-400bts/min | 250-500bts/min |
| Stoppling qualification rate | >=99% | |||||
| Laminar air cleanliness | 100 grade | |||||
| Vacuum pumping speed | 10m3/h | 30m3/h | 50m3/h | 60m3/h | 60m3/h | 100m3/h |
| Power consumption | 5kw | |||||
| Power supply | 380V 50Hz | |||||
Production procedures:
1.The compact line realizes single linkage, continuous operation from washing, sterilizing& drying,filling& stoppering, and capping. The whole production process realizes cleaning operation; protects products from contamination, meets the GMP production standard.
2.The whole line adopts PLC total control, frequency converter, touch screen control technology, stable and reliable operation.
3.Each machine has a power-off restart data saving function
4.Ultrasonic washing CIP station for the mesh belt of sterilizer
5.No vial no filling, no vial no stopper supply, no vial no capping
6.Automatically reject for the unqualified vials
7.Machine adopts superior SS 316L for part in product contact with product/drugs design to ensure cleaning and no dead angles
8.Industrial PC control with state of art features for Audit trail, data integrity, Graphical debugging and remote access
