Antimicrobial peptide LL-37, belonging to the cathelicidin family, is the first amphipathic alpha-helical peptide isolated from human. It plays an important role in the first line of defense against local infection and systemic invasion of pathogens at sites of inflammation and wounds. Cytotoxic to both bacterial and normal eukaryotic cells , LL-37 is significantly resistant to proteolytic degradation in solution.
Chemistry | |
Sequence one letter code |
|
---|---|
Sequence three letter code |
|
CAS registry number |
|
Molecular Formula |
|
Molecular Mass/ Weight |
|