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Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2
Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2
Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2
Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2
Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2
Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2

Factory Sell Weight Loss GMP Retatrutide GLP-1 Peptides Semaglutide Tirzepatide Powder CAS 2381089-83-2

Min.Order: 1
Product origin: Hangzhou, Zhejiang, China
Infringement complaint: complaintComplaint
US$ 20 ~ 30

Description

Product Description

GLP-1 Wholesale.
Semaglutide, Tirzepatide, Retatrutide, NAD, GHK-CU, Melanotan, Polypeptide  
5mg 10mg 15mg 20mg 30mg 1g
 
Our Advantages: High purity, Wholesale price, large stock, Stealth Shipping, 100% Delivery Guarantee
Common NameLY3437943
CAS Number2381089-83-2Molecular Weight4731.33
DensityN/ABoiling PointN/A
Molecular FormulaC221H342N46O68Melting PointN/A
MSDSN/AFlash PointN/A
Products Name: Retatrutide
CAS No.: 2381089-83-2
Purity: >99.0%
Molecular Formula: C187H291N45O59
Molecular Weight: 4113.64g/mol
Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18diacid-γ-Glu-OEG-OEG)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Appearance: White Lyophilized powder
Reconstitution: Required 
Storage:After reconstitution store at 2°C - 8°C

What is Retatrutide ?

Retatrutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to semaglutide,tirzepatide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans

Product Benefits:
  • Weight loss 
  • Anti-diabetes
  • Alzheimer's disease.
 
 

Main Products

How is Retatrutide different from Semaglutide and Trizepatide ?
Mechanism:
1. Semaglutide work as (GLP-1) hormone agonist.
2. Tirezepatide work as (GLP-1 & GIP ) hormone agonist.
3. Retatrutide work as (GLP-1 & GIP & Glucagon) hormones agonist.

Weight loss in trials:
1. Semaglutide led to a 6-12% reduction in body weight in 28 weeks
2. Tirezepatide led to a 15-20% reduction in body weight in 72 weeks
3. Retatrutide led to a 25% reduction in body weight in 48 weeks

Weight Management
Indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of ≥30 kg/m2 (obesity) or ≥27 kg/m2 (overweight) in the presence of at least 1 weight-related comorbid condition (eg, hypertension, type 2 diabetes mellitus, dyslipidemia)
Initiate with low dose and gradually escalate to maintenance dose of 2.4 mg/week SC to minimize GI adverse reactions
If unable to tolerate a dose during escalation, consider delaying dose escalation for 4 weeks
If unable to tolerate maintenance dose of 2.4 mg once-weekly, may temporarily decreased to 1.7 mg once weekly, for a maximum of 4 weeks; after 4 weeks, increase back to maintenance 2.4 mg once-weekly; discontinue if not tolerated after second attempt
In patients with type 2 diabetes, monitor blood glucose before initiating and during treatment
Once weekly SC dose escalation schedule:
Weeks 1-4: 0.25 mg
Weeks 5-8: 0.5 mg
Weeks 9-12: 1 mg
Week 13-16: 1.7 mg
Week 17 and onward: 2.4 mg (maintenance)
Product No.Product
45051511Semaglutide 5mg
45051512Semaglutide 10mg
45051513Semaglutide+Vitamin B12
45051514Semaglutide+Vitamin B6
45051515Semaglutide+L-Carnitine
45051516Semaglutide cartridges 5mg
45051517Semaglutide cartridges 10mg
45051518Setmelanotide 20mg
45051519Tirzepatide 5mg
45051520Tirzepatide 10mg
45051521Tirzepatide 15mg
45051522Tirzepatide 20mg
45051523Tirzepatide 30mg
45051524Tirzepatide+Vitamin B12
45051525Liraglutide 10g
45051526Retatrutide 8mg
45051527Retatrutide 10mg
45051528Retatrutide 12mg
45051529Orforglipron 1g
45051530Mazdutide 1g
45051531NAD+ 500mg
45051532NAD+ 750mg
45051533NAD+ 1000mg
45051534NMN 150mg
45051538Adipotide/FTPP 10mg
45051539α-Klotho (Alpha Klotho) 50µg
45051541A960 5mg
45051542ARA-290 16mg
4505154357 5mg
4505154457 10mg
45051545B7-33 5mg
45051546cAC-253 (Cyclic AC-253) 10mg
45051549DSIP 5mg
45051550DSIP 10mg
45051551Epitalon 10mg
45051552Epitalon 20mg
45051553Epitalon 100mg
45051554FG loop (FGL) 10mg
45051556F344 1mg
45051557FOXO4-DRI 10mg
45051559GHK-Cu (Copper Peptide) 50mg
45051560GHK-Cu (Copper Peptide) 100mg
45051561G2 10mg
45051562G6 10mg
45051563Gona 10mg
45051564HC5000
45051565Hexa 2mg
45051566Hexa 5mg
45051568Humanin 10mg
45051573Ipam 5mg
45051575Kisspeptin-10 5mg
45051576Kisspeptin-10 10mg
45051577KPV 5mg
45051578KPV 10mg
45051579LL-37 (CAP-18) 5mg
45051580Melanotan 1 10mg
45051581Melanotan 2 10mg
45051582MOTS-c 5mg (acetate, TFA removed)
45051583MOTS-c 10mg  (acetate, TFA removed)
45051584N-Acetyl Epitalon Amidate 10mg
45051585N-Acetyl Selank Amidate 10mg
45051586N-Acetyl Semax Amidate 30mg
45051587Oxytocin 10mg
45051588PNC-27 5mg
45051590P21 (P021) 5mg
45051591Selank 10mg
45051592Semax 10mg
45051593Sermo 2mg
45051594Sermo 5mg
45051595SS-31 40mg
45051596Taltirelin 10mg
45051597Tesam 2mg
45051598Tesam 5mg
45051600Thymalin 20mg (63958-90-7)
45051601Thymosin Alpha-1 3mg
45051602Thymosin Alpha-1 5mg
45051603Thymosin Alpha-1 10mg
45051604Thymosinb4 5mg
45051605Thymosinb4 10mg
45051607TP508 Thrombin Peptide 10mg
45051608TRH Thyrotropin (Protirelin Acetate) 20mg
45051609VIP (Vasoactive Intestinal Peptide) 6mg
45051610Bronchogen (Bronchi) 20mg
45051611Cardiogen (Myocardium) 20mg
45051612Cartalax (Joints) 20mg
45051613Chonluten (Respiratory organs) 20mg
45051614Cortagen (Brain) 20mg
45051615Crystagen (Immune system) 20mg
45051616Livagen (Liver) 20mg
45051617Pancragen (Pancreas) 20mg
45051618Pinealon (Brain) 20mg
45051619Prostamax (Prostate) 20mg
45051620Testagen (Testes) 20mg
45051621Vesugen (Blood vessels) 20mg
45051622Vilon (Eye retina) 20mg
45051623B15, T50 Blend 10mg

Company Profile

ZB Bio has a long-standing track record in with successful registrations of highly purified synthetic peptide drugs of the glucagon family. Our regulatory intelligence keeps track of important changes in the relevant legislation. This enables us to be a leading global innovator in the field of glucagon and glucagon-like synthetic peptide drugs. Our services have been optimized to shorten timelines and of reduce complexity for our clients.

Our high-tech Good Manufacturing Practice (GMP) facilities based in Zhejiang province china, plus the commitment of our technical and scientific experts to quality, are the cornerstones for continuous compliance. We deliver small-scale to multi-kg active pharmaceutical ingredients (APIs) with impurities below 0.5%, identification and characterization of impurities above 0.10% using orthogonal analytical techniques.

OPTIMIZED, AUTOMATED HIGH-YIELD PRODUCTION

Our long experience in complex APIs allows us to optimize the processes for high yields at outstanding quality. Our high level of process automation allows for cost-efficient and large-scale production resulting in excellent overall material purity (>99.5%). Innovative solutions like continuous chromatography let us use equipment and resources more efficiently and help us and our partners to achieve their commitment to sustainability and environment-friendly production.

OUR TIMELINES FOR SEMAGLUTIDE

ROBUST PROCESSES AND SUPPLY SECURITY

Having our in-house building blocks for peptide synthesis as well as long-term cooperation with trusted suppliers ensures on-time production. Redundancy of multi-purpose equipment and facilities helps to mitigate risks in the supply chain, together with our stock of finished APIs and is the key for on-time product deliveries to our customers.

RELATED PRODUCTS (FOR RESEARCH PURPOSES ONLY)

Beyond GMP-grade semaglutide, we provide semaglutide in research grade, variants thereof and in different salt forms.

 

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