Description
Product Name: Abiraterone acetate
Synonyms:
Abiraterone Acotate;Abiraterone Acetate impurity;
(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate;[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;(3β)-17-(3-pyridinyl) androsta-5,16-dien-3-yl acetate;
Abiraterone acetate, >=99%;
Abirteroneacetate;
ZYTIGA
CAS: 154229-18-2
MF: C26H33NO2
MW: 391.55
EINECS: 620-314-7
Product Categories: Inhibitors;Inhibitor;API;DQM;Final material;Anti-cancer & immunity;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;154229-18-2
Mol File: 154229-18-2.mol
Melting point 127-130°C
Boiling point 506.7±50.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Chloroform (Slightly), DMSO (Sparingly), Methanol (Sparingly)
pka 5.31±0.12(Predicted)
form powder
color white to beige
WGK Germany 3
RTECS BV7992100
HS Code 2937290000
Identification | Infrared absorption <197K> | Conforms |
| The retention time of the major peak of the Sample solution corresponds to that in the chromatogram of the standard solution | |
Related Substances | α-Epoxyabirater-one acetate ≤0.25% β-Epoxyabirater-one acetate ≤0.25% Abiraterone≤0.20% Abiraterone ethyl ether≤0.20% Abiraterone isopropyl ether≤0.20% Unspecified impurity≤0.10% Total impurity≤0.80% | Not detected Not detected Not detected 0.02% Not detected 0.02% 0.09% |
Water | ≤0.25% | 0.08% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metal | ≤10ppm | Conforms |
Assay (as-is basis) | 98.0%-102.0% | 99.5% |
Conclusion:The product conforms to the USP43 standard |