Description
Products Name: Semaglutide
CAS No.: 910463-68-2
Purity: >99.0%
Molecular Formula: C187H291N45O59
Molecular Weight: 4113.64g/mol
Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18diacid-γ-Glu-OEG-OEG)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Appearance: White Lyophilized powder
Reconstitution: Required
Storage:After reconstitution store at 2°C - 8°C
What is Semaglutide ?
Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015).
The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position
2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans
Product Benefits:-Slows down how quickly food leaves your stomach, leaving you with a feeling of fullness and satisfaction with smaller meals.
-Lowers blood sugars, in part by reducing the production of sugar in the liver.
-Slows Intestinal motility (movement of food from mouth out of the body.
Our advantages:Goods quality- Product has COA, and HPLC report
- Our factory is ISO9001 standard
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OEM service- Add customer's logo
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- Cap color can be customized
Shipping service- Goods shipped in 2-7 days after get payment.
- Small order ship by express door to door.
- Goods arrive in 7-20 days
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