Cascara Sagrada Bark Extract Introduction:
Cascara sagrada (Rhamnus purshiana) is a shrub native to western North America,its bark is processed for medicinal purposes.Cascara sagrada contains organic plant compounds called anthraquinones that have powerful laxative effects.
Cascara sagrada bark extract is primarily used to treat constipation.The anthraquinones contained in the bark inhibit the absorption of water and electrolytes in the intestines. Because of this,stool volume increases as it absorbs the excess water,which increases pressure within the intestine.This stimulates muscle contractions in the colon (peristalsis),speeding the clearance of the bowel.
Cascara sagrada is considered a stimulant laxative alongside other natural laxatives like aloe vera and senna.Unlike these counterparts,the effect of cascara sagrada tends to be gentler,resulting in fewer loose or watery stools.Cascara sagrada also works differently than demulcent laxatives like psyllium,which creates a gel-like substance that helps ease stool from the bowels.
Application:
1. Treating constipation
2. Cleansing colons effect
3. Increasing peristalsis in the large intestine and help restore its tone
4. Preventing the pressure and pain associated with hemorrhoids and anal fissures
Product Name | Cascara Sagrada Bark Extract | Batch Number | CSE-210917 | ||||
Botanical Source | Rhamnus purshiana L. | Batch Quantity | 475kgs | ||||
Plant Part Used | Bark,100% Natural | Country of Origin | China | ||||
Type of Product | Standard Extract | Active Ingredient Markers | Cascarosides | ||||
Analysis Items | Specifications | Results | Methods used | ||||
Appearance | Fine brown-yellow powder | Conforms | Visual test | ||||
Odor & Taste | Characteristic, bitter | Conforms | Organoleptic test | ||||
Bulk Density | 35-45g/100ml | Conforms | ASTM D1895B | ||||
Particle Size | 99% through 80 mesh | Conforms | AOAC 973.03 | ||||
Solubility | Partially soluble in hydro-alcoholic solution | Conforms | Visual | ||||
Assay (as Cascaroside A) | NLT Cascarosides 10% | 10.62% | UV-VIS | ||||
Loss on Drying | NMT 5.0% | 3.06% | 5g /105ºC /2hrs | ||||
Ash Content | NMT 10.0% | 2.13% | 2g /525ºC /3hrs | ||||
Extract Solvents | Ethanol & Water(80% v/v) | Conforms | / | ||||
Solvent Residues | NMT 0.01% | Conforms | USP-GC | ||||
Heavy Metals | NMT 10ppm | Conforms | ICP-MS | ||||
Arsenic (As) | NMT 2ppm | Conforms | ICP-MS | ||||
Lead (Pb) | NMT 2ppm | Conforms | ICP-MS | ||||
Cadmium (Cd) | NMT 0.1ppm | Conforms | ICP-MS | ||||
Mercury(Hg) | NMT 0.1ppm | Conforms | ICP-MS | ||||
BHC | NMT 0.1ppm | Conforms | USP-GC | ||||
DDT | NMT 0.1ppm | Conforms | USP-GC | ||||
Acephate | NMT 0.2ppm | Conforms | USP-GC | ||||
Methamidophos | NMT 0.2ppm | Conforms | USP-GC | ||||
Parathion-ethyl | NMT 0.2ppm | Conforms | USP-GC | ||||
PCNB | NMT 0.1ppm | Conforms | USP-GC | ||||
Aflatoxins | NMT 0.2ppb | Absent | USP-HPLC | ||||
Sterilization Method | High temperature & pressure for a short time of 5~10 seconds | ||||||
Microbiological Data | Total Plate Count < 10,000cfu/g | < 1,000 cfu/g | GB 4789.2 | ||||
Total Yeast & Mold < 1,000cfu/g | < 100 cfu/g | GB 4789.15 | |||||
E. Coli to be absent | Absent | GB 4789.3 | |||||
Staphylococcus to be absent | Absent | GB 4789.10 | |||||
Salmonella to be absent | Absent | GB 4789.4 | |||||
Packing and Storage | Packed in fiber drum, LDPE bag inside. Net weight: 25kgs/drum. | ||||||
Keep tightly sealed, store away from moisture, strong heat and sunlight. | |||||||
Shelf Life | 2 years if sealed and stored in the recommended conditions. |