Vitamin K2 is essential for the carboxylation of glutamate residues in certain proteins, to give-carboxyglutamate. This modification allows the protein to bind calcium, an essential event in the blood clotting cascade. Carboxylation of glutamate is also important in other proteins involved in the mobilization or transport of calcium. Vitamin K2 is also a known of SXR. Currently in Japan, Vitamin K2 is being used to treat the degenerative bone disease osteoporosis.Vitamin K2 is a fat-soluble vitamin,it is needed to manufacture prothrombin, a substance essential for the normal clotting of blood.