Complaint
Basic Info
Product Name: Mirtazapine
CAS NO.: 85650-52-8
Molecular Formula: C17H19N3
Molecular Weight: 265.35
Purity: 99%
Appearance: White Powder
Grade: Pharmaceutical Grade
Product Description
Mirtazapine (brand names: Avanza, Axit, Calixta, Mirtaz, Mirtazon, Remeron, Zispin) is an atypical antidepressant with noradrenergic and specific serotonergic activity. It blocks the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizes the 5-HT2 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) introduced by Organon International in the United States in 1996, and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA) and is the 6-aza analogue of mianserin. It is also racemic-occurs as a combination of both (R)-(−)- and (S)-(+)-stereoisomers, both of which are active.
Application:
Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.
COA:
| Items | Standard | Result |
| Appearance | White or off-white powder | Complies |
Identification | The IR absorption spectrum is accordant with the spectrum obtained with CRS | Complies |
| Solubility | , Practically insoluble in water,freely soluble in anhydrous ethanol | Complies |
specific rotation | -0.10°~+0.10° (anhydrous substance) | +0.001° |
| Water | ≤3.5% | 2.8% |
| Sulfated ash | ≤0.10% | 0.04% |
| granularity | 80%<75 m | 39.28 m |
| Residual solvents | Ethanol ≤5000ppm | 130ppm |
Impurity | Impurity A A≤0.10% | ND |
| Impurity B B≤0.10% | ND | |
| Impurity C C≤0.10% | ND | |
| Impurity D D≤0.10% | ND | |
| Impurity E E≤0.10% | ND | |
| Impurity F F≤0.10% | ND | |
| Individual impurity ≤0.10% | ND | |
| Total impurities ≤0.20% | ND | |
Microbial limit test | aerobic bacteria≤1000CFU/g | <10CFU/g |
| fungus≤1000CFU/g | <10CFU/g | |
| Absence of escherichia coli | ND | |
| Assay | 99.0~101.0%(anhydrous substance) | 100.0% |
| Conclusion | Complies to EP7.0 | |
Packing and Shipping
Company Introduction
Wuhan HaileruiTechnology Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
FAQ:
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
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Factory Lowest Price Chemical Raw Materials 99% Pure CAS: 85650-52-8 Mirtazapine
