Marya Pharmaceutical Plastic Bottle Blowing Filling Sealing Porduction Line for Eye-Drop Ear-Drop IV Fluid Preparation Packing

   Plastic bottle blow fill seal machine (BFS machine for short) is an advanced technology that integrates molding, filling and sealing under complete control, which enables liquid to be packaged in polypropylene/high-density & low-density polyethylene plastic bottles, and the whole production process automatically completes the followings in a controlled environment (aseptic environment):
***Extrude plastic particles into plastic pre-form at high temperature.
***Then the preform is blown into a container by sterilized and filtered air.
***Filling liquid that has been sterilized and filtered.
***Tight sealing of containers after filling.


 

Performance Features
 

1, The design, MOC, manufacturing, assembly and debugging of the BFS machine meet the requirements of the new GMP standards for drug production.
2, The plastic bottle blow fill seal machine has advanced equipment, unique and reasonable structure, and stable and reliable 
performance.
3, Applicable Specification: 0.2ml-1000ml plastic bottle (as per user's requirements).
4, Production Capacity: 1000-18000BPH.
5, The number of bottles made each time: 1-30 bottles/mould, can be selected based on production capacity.
6, Filling Accuracy: ≤ ±1% (according to drug characteristics)
7, The BFS machine is integrated with bottle-making, filling and sealing, with compact structure and occupies small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
8, The plastic particles are plasticized by a low-speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
9, Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
10, Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on man-machine interface.
11, High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
12, For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
13, The filling system is accurately calculated by time pressure method with high filling precision, which can meet filling range of 0.2ml-2000ml to ensure production speed.
14, The equipment has black and white sections, the moving parts are isolated in non-clean are(black area), and only the basic components and operations are kept in clean area(white area), which reduces the area of clean room and the number of particles in clean room.
15, Automatic in-place cleaning / in-place sterilization function (CIP/SIP) can be realized. 
16, Configurable on-line monitoring system for dust particles and plankton bacteria.
17,  In the process of bottle transfer, the inner surface of interface is not in contact with parts, which eliminates the produce of visible foreign matter.
18, The whole blow fill seal technology can realize fully automatic control and monitor of production process, high precision color touch screen operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation and other control technology are used.
19, The products can be customized according to the actual demand of customers.

vial liquid filling machine