CAS: 13422-55-4 Vitamin B12 Mecobalamin Powder Methylcobalamin

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Product origin: Xi'an, Shaanxi, China

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US$ 2500 ~ 3500

Description

Cas:13422-55-4 Mecobalamin powder vitamin B12

Product Name	Mecobalamin
Appearance	Red powder
Assay	10%,20%,40% water soluble,98% fat-soluble Mecobalamin
CAS No.	13422-55-4
Molecular Formula	C₆₃H₉₁CoN₁₃O₁₄P
Molecular Weight	1344.382
Melting point	>190°C (dec.)
Grade	Medicine Grade
Test Method	HPLC
Storage	Store in cool and dry place,keep away from strong light.
Shelf life	2 years when properly stored.

Mecobalamin is an organic compound with chemical formula C63H91CoN13O14P and endogenous vitamin B12. It exists in blood and pulp fluid. Compared with vitamin B12, Mecobalamin has a good effect on the conduction of neurons and can promote nucleic acid-protein-fat metabolism through methyl conversion reaction. As a coenzyme of methionine synthetase, it can convert homocysteine into methionine, participate in the process of deoxyriboside synthesis of thymine, promote nucleic acid and protein synthesis, promote intra-axonal transport and axonal regeneration and myelin formation, prevent axonal degeneration and repair damaged nerve tissue.
Methylcobalamin is a form of vitamin B12. It is used to treat megaloblastic anemia caused by vitamin B12 deficiency and is also used in peripheral neuropathy.

Item of Analysis	Specification	Results	Test Methods
Assay(on the anhydrous basis )	98%~101%	99.20%	HPLC
Appearance	White powder	Conform	Visual
Identification
A: IR	Corresponds qualitatively to the reference	Complies	USP41-NF36
B: Color Reaction	A blue color appears	Positive	USP41-NF36
Water(KF)	≤0.2%	0.03%	USP41-NF36
Residue on ignition	≤0.1%	0.02%	USP41-NF36
Mesh size	Not less than 90% pass 80 mesh	Complies	80 mesh screen
Residual Solvents	Ethanol ≤1000ppm	18ppm	USP41-NF36
Heavy metals	Inorganic arsenic ≤3μg/g	0.06μg/g	USP41-NF36
	Total Hg ≤3μg/g	<0.01μg/g	USP41-NF36
	Lead ≤1μg/g	0.09μg/g	USP41-NF36
Chromatographic purity	Test 1: Coenzyme Q7,Q8,Q9,Q11 and related impurities:≤1.0% Test 2: 2Z isomer and related impurities:≤1.0% Test 1 & Test 2: ≤1.5% Test 3: The single related impurities≤0.3%	0.37% 0.05% 0.42% 0.25%	USP41-NF36
Total Plate Count	≤1000cfu/g	<10 cfu/g	USP41-NF36
Yeast & Mold	≤100cfu/g	<15 cfu/g	USP41-NF36
E. Coli.	Negative	Negative	USP41-NF36
Salmonelle	Negative	Negative	USP41-NF36
S.aureus	Negative	Negative	USP41-NF36

Storage: 0-25ºC, preserve in well-closed, light-resistant container.Keep out of directly light and away from heat source.
Shelf life: 36 months if store under the conditions above and stay in original packaging.

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