Complaint
Apalutamide is a white powder, Apalutamide is an androgen receptor antagonist with potential antineoplastic activity. Apalutamide binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. Apalutamide prevents binding to and transcription of AR-responsive genes. Apalutamide ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells.
Product Name: Apalutamide;ARN-509
CAS: 956104-40-8
MF:C21H15F4N5O2S
MW:477.43
EINECS:807-449-9
MDL No.:MFCD22380626
Density 1.59±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥23.85 mg/mL in DMSO; insoluble in H2O; ≥7.33 mg/mL in EtOH
form solid
Purity: 99%
Package: 100g;1kg;25kg
| Chemical and Physical Properties | |
| Appearance | White powder |
| Solubility | Dichloromethane, Tetrahydrofuran |
| Quality standard | CHINA GMP |
| Application | |
| Drug Indication/Application/Use | ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment |
| Formulations/Preparations | androgen receptor inhibitor |
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods | Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed | Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
