Star products in JANUARY 2022--HyperChem | |
Identification | |
Name | D-α-Tocopherol Succinate |
Other Name |
4345-03-3 alpha-Tocopheryl succinate D-alpha-Tocopherol succinate tocopherol succinate |
CAS number | 4345-03-3 |
Molecular Formula | C33H54O5 |
Molecular Weight | 530.78 |
EINECS | 224-403-8 |
Chemical and Physical Properties | |
Appearance | White powder |
Storage | 76 °C |
Quality standard | CP/USP |
Application | |
Drug Indication/Application | Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. Moreover, manufacturers typically convert the phenol component of the vitamin to esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and easier to use in vitamin supplements. Alpha-tocopherol succinate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years. Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more. At the moment, however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use. Moreover, although it is generally believed that alpha-tocopherol succinate would naturally demonstrate such general vitamin E-tocopherol pharmacodynamics after undergoing a logical de-esterification in the gut, there is ongoing research that proposes that the alpha-tocopherol succinate compound itself is capable of eliciting anti-cancer and inflammation mediation activities that are unique from the alpha-tocopherol form and other alpha-tocopherol esters. |
Formulations/Preparations | Tablet Powder for Suspension Tablet, Chewable Tablet, Extended Release Capsule |
Handling and Storage | |
Safety and Hazards | The Shanghai Research Institute of Chemical industry testing center identification conclusion :1 No hazard identification, 2 The substance is not subject to IATA DGR, 3 Nonpacking requirements. |
Handling and Storage | Store at a controlled room temperature 20 -25°C (68 -77°F) |
Sample package | Double plastic bags inside, aluminum foil bag outside |
Commercial package | Double plastic bags inside,5kg, 10kg, and 25kg fiber drum outside. |
UN Code | Not classified |
HS Code | 2936280000 |
Shipping group | Shipment at ambient temperature for no controlled and no dangerous goods |
Sales restriction | No |
Origin | China |
Technnical support | |
D-α-Tocopherol Succinate,STD Data sheet D-α-Tocopherol Succinate,MSDS D-α-Tocopherol Succinate,COA D-α-Tocopherol Succinate,Transport Certificate | Yes Yes Yes Yes |
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