Capecitabine CAS 154361-50-9 for Breast Cancer and Colorectal Cancer

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Product origin: Xi'an, Shaanxi, China
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US$ 260 ~ 400

Description
Capecitabine CAS 154361-50-9 for Breast Cancer and Colorectal Cancer

Specification of Analysis

Product NameCapecitabine 
AppearanceWhite powder
Molecular formulaC15h22fn3o6
Molecular Weight359.35
CAS154361-50-9
Melting Point110-121°C

What is Capecitabine?

Capecitabine is rapidly absorbed by the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5' fluorocytidine in the liver by carboxyl esterase, followed by cytidine removal from liver and tumor tissues. The action of the aminoase is converted to 5'-deoxy-5' fluorouridine and finally catalyzed by thymidine phosphorylase to fluorouracil (5-FU) in tumor tissues.Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration is significantly higher than that of blood and muscle. The efficacy of tumors in a variety of animals was significantly higher than 5-FU.

Function

1.Colorectal Cancer (either as neoadjuvant therapy with radiation, adjuvant therapy or for metastatic cases)
2.Breast cancer (Metastatic or as monotherapy/combotherapy, this is licensed as a second-line treatment in Uk)
3.Gastric Cancer (off-label  in the US, this is licensed indication in UK)
4.Oesophageal Cancer (off-label in US)

Application

Anticancer drugs are mainly used for non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer and other solid tumors.

 

 
 
 
 
 
 
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