Complaint
Tryptamine powder is an amino acid product with an indole ring structure. lts chemical system comprises fused benzene,pyrrole ring, and 2-aminoethyl group. This structure is related to the products melatonin, serotonin, and Aminergic neuromodulators such as 5-methoxytryptamine share standard features to some extent.
Tryptophan is an amine formed from the decarboxylation of tryptophan, which is formed by oxidation by amine oxidase.lt is a joint functional group in compounds called collectively substituted tryptamines.It exists in the mammalian brain andacts as a neuromodulator or neurotransmitter. Like other trace amines, tryptamine binds to the human trace amine-related receptor TAAR1 as an agonist. 5-Hydroxy derivatives are present in mammalian plasma and amphibian skin andhave vasoconstriction effects.
Tryptamine is an essential biochemical reagent and an important raw material for synthesizing indole compounds.Aconsiderable part of the alkaloids extracted and isolated from natural plants are indole alkaloids. With the slow reductionof wild plants and the high extraction cost, synthesizing these alkaloids has become a top priority.Tryptamine is the
crucial raw material for synthesizing these alkaloids. We can provide raw tryptamine.
At present, there are two origins of the molecular formula of tryptamine in the industry:
1) with diethyl malonate through addition, reduction, then condensation, then diazotization,cyclization, and decarboxylation obtain the target product tryptamine;
2)Take indole as starting material, obtain indole aldehyde through the Vilsmeier reaction, to get 3-(2-nitro vinyl) indole, and obtain target tryptamine through catalytic hydrogenation.
| Certificate Of Analysis | ||
| ltem | Specification | Results |
| Assay | ≥98.0% | 99.65% |
| Description | White to light-yellow crystalline powder | Complies |
| Melting point | 113-116C(lit.) | Complies |
| Solubility | Water: soluble1g/Lat 20°ºC | Complies |
| Loss on drying | ≤0.50% | 0.04% |
| Residue on ignition | ≤0.50% | 0.22% |
| Heavy Metals | ≤20ppm | Complies |
| Total Plate Count | ≤1000cfu/g | Complies |
| Yeast & Mold | ≤100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
What ls Tryptamine Used For
1.Tryptamine is an agonist of hTAAR1hTAAR1 is a stimulatory Gprotein-coupled receptor, and studies are currentlyexamining the depressive activity, cognitive enhancement, stress reduction, and anti-addiction effects of hTAAR1activation.This role could be considered a way to treat depression, addiction, and schizophrenia.Tryptamine can modulate the balance between inhibitory and excitatory activation of hTAAR1 in neural activity.It acts as a nonselectiveserotonin receptor agonist and serotonin-norepinephrine-dopamine releaser, and it inducesthe release of serotonin anddopamine more readily than norepinephrine. In psychotropic drugs,tryptamines are a large class of classic halucinogens.
2.Tryptamine can promote intestinal peristalsis Tryptamine produced by commensal bacteria in the human gut activatesa ubiquitously expressed serotonin GPCR in colonic epithelial cells.After tryptamine binds to the serotonin receptorGPCR, the activated 5-HT4 receptor changes, this means that theGs a subunit will be exchanged from GDP to GTP, andGTP can bind Gs to activate adenylyl cyclase, which catalyzes the conversion of ATP to cyclic adenosine monophosphate(cAMP).cAMPopens chloride and potassium channels, drives colonic electrolyte secretion, and promotes intestinalperistalsis.
In addition, tryptamine can serve as a feedstock for metabolic pathways affecting plant growth and microbial communities. For example, it was to be a possible intermediate in the biosynthetic pathway of the plant hormone indole-3-acetic acid. lt is a noncompetitive inhibitor of serotonin N-acetyltransferase in mosquitoes. SNAT catalyzes the anabolism of serotonin to N-acetylserotonin, a neuromodulator and immediate precursor of melatonin.
Wuhan Ability Chemical Technology Co., Ltd., a holding subsidiary founded in Wuhan by Luotian Xinpusheng Pharmaceutical Co., Ltd., is mainly engaged in the technical development and sales of pharmaceutical and chemical products.
Our factory, Luotian Xinpusheng Pharmaceutical Co., Ltd., has 28 patents for independent research and development, and has successively won the Golden Eagle Award for National High- tech Enterprise, Provincial Invisible Champion Enterprise, Provincial Specialized, Refined, Featured and Innovative "Little Giant" Enterprise, Top 100 Enterprise and Excellent Enterprise in Huanggang. Our process Technology centers and highly flexible GMP-compliant production assets is dedicated to delivering successful outcomes for you.
At present, the company business scope involves 3 areas: Health ingredients / Foods & Feedstuff Additives, APIs and Pharmaceutical intermediate. The main products are Melatonin, DIM and Chrysin, which are exported to many different clients in the Food & Beverage, Cosmetics, Pharmaceutical and Health industries. Adhering to the principle of "quality, credit paramountcy, service and mutual benefit first", we wholeheartedly serve new and regular customers in European, American and other countries all over the world.
Wuhan Ability Chemical Technology Co., Ltd is always looking for environment friendly and "green" opportunities for its products and principles. We stand for long-term relationships with our clients and high-quality service. Would you like more information about our services as Melatonin suppliers or would you like to request a sample of Melatonin? Please do not hesitate to contact us.
1. With a seasoned R&D team, we are experienced in producing multiple chemicals over
the past ten years.
2. Tailor-made packing can also be available according to your specific requirements.
3. Fast response. Every inquiry will be answered within 24 hours.
4. Prompt delivery. We have worked with many forwarding companies for years.
Q: When will my goods be shipped?
A: About 3~5 days after prepayment is paid.
Q: Can I get a sample?
A: Free samples are available, but buyers need to pay freight.
Q: How long does it take for me to get a sample?
A: It depends. Generally speaking, it is about 7-10 days.
Q: Why is the quote offered different from the sticker price?
A: As we know, prices of chemicals are not fixed, they fluctuate with the markets.
Q: Is the quality of your products guaranteed?
A: We have a professional R&D team, so every batch of our products is up to standard.
