Purity 99% Na-Epithalon/Na-Epithalon-Nh2/ Epithalon Epitalon Peptide Powder CAS No.: 307297-39-8

High Purity 99.0%min. Epithalon Epitalon Peptide Powder  CAS NO.:307297-39-8
 

Description:

Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. This pineal peptide preparation is secreted in the epithlamium-epiphyseal region of the brain. Its more prominent tasks are: to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epithalamin increases a person's resistance to emotional stress and also acts as an antioxidant.

Epithalamin was first discovered in the late 1980's by Prof. Vladimir Khavinson from St. Petersburg, Russia. It has been studied extensively ever since. It is known by several names, including Epitalon, Epithalon, Epithalone, Epithalamin and Epithalamine. Since all the patents are held by the Russian inventor there is not much interest for this tetra-peptide from the western big pharma industry. This makes the substance fairly unknown in the west due to the absence of marketing usually seen with big pharma products. In Russia it is currently in clinical studies and shows prospective results as treatment for liver disorders, neuropathology, psychiatry and geriatrics. 


Application:

Epitalon decreases the age-related changes in immune and neuroendocrine systems,reduces the incidence of recurrent infections and chronic diseases. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems.Results of 12-months treatment with Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems. Elevated uric acid, alkaline phosphatase and cholesterol in elder patients returned to normal after 10 days of treatment, and remained stable in a several months peroid 

Epitalon benefit:

1. Increases lifespan
2. Boosts energy levels
3. Improves skin appearance
4. Helps heal injured muscle cells
5. Promotes deeper and more restful sleep
6. Delays or prevents age-related heart disease, cancer and dementia
7. Tumor prevention (inhibition of cancer cells due to protective effect of elongated telomeres)


Epitalon dosage:

Due to the short length of the amino-acidic chain, Epitalon is administrated orally, nasal spray drops or injectable (by far the most effective method) in 10 - 20 days-in-row cycles.
Oral administration: 2 - 8 mg/day, 2 - 3 servings per day
Nasal administration: 1 - 5 mg/day, 3 servings per day
Injectable administration: 0.5 - 3 mg/day, 1 - 2 injections per day (intramuscularly or subcutaneously)
 

Reconstitution and storage:

Epitalon comes as a lyophilized powder. It is recommended to inject 1 - 2ml of sterile or bacteriostatic water into the vial and mix gently.

Storage:

Powder Form: Product may be stored up to 90 days at room temperature when in powder form. Shelf life 2 years when frozen (recommended) or kept refrigerated below 8o C (46o F).

Once Reconstituted To Liquid:

 Product may be stored at room temperature (cool dark location) up to 10 days. Highly recommended to keep product refrigerated below 8o C (46o F). Do not freeze once reconstituted.

What is Snap-8?

Acetyl Glutamyl Heptapeptide-3 or Acetyl Octapeptide-1 (or -3) (SNAP-8) is scientifically and   reasonablely designed of anti-wrinkle active ingredients of polypeptide. It has a similar role to   Essence and has become one of the most popular raw materials around the world for   upscale anti-wrinkle cosmetics.Anti-wrinkles caused by the contraction of muscles of facial   expression, decreasing neuronal excitability by SNARE complex destabilisation.

 Snap-8, this ingredient contains eight amino acids and (hence the "Octa") has the same           
(some say  much better) anti wrinkle qualities . Snap-8 produced roughly 35%   reduction in wrinkle   depth.

Storage
Common storage 2-8ºC, long time storage -20ºC.

Functions
Anti-wrinkles caused by the contraction of muscles of facial expression, decreasing neuronal excitability by SNARE complex destabilisation.
Anti-aging which caused by mobile face.removing the deep lines or wrinkles in the forehead or around the eyes area.

Background
SNAP-8 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles.