Manufacturer of Veterinary API CAS 1264-72-8 Colistin Sulfate

Min.Order: 1

Product origin: Qingdao, Shandong, China

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US$ 10 ~ 30

Description

Colistin Sulfate, also known as colistin, polymyxin E, antibiotics, etc., is a white or nearly white powder, odorless, bitter, and hygroscopic. It is easily soluble in water, slightly soluble in methanol, ethanol, and almost insoluble in acetone, ether, etc. It is also slightly soluble in water when it is free from alkali. Stable within the range of PH3-7.5. Sulfuric colistin is produced by polymyxin and has a strong antibacterial effect on Gram negative bacteria. It is used to treat intestinal diseases caused by Gram negative bacteria, as a feed additive, and has a significant growth promoting effect. It works well when combined with sulfadiazine.

ITEMS	SPECIFICATION	RESULT
DESCRIPTION	WHITE OR ALMOST WHITE POWDER	WHITE POWDER
IDENTIFICATION	COMPLIES	COMPLIES
PH VALUE	4.0~6.0	4.6
LOSS ON DRYING	≤3.5%	1.8%
(DRIED SUBSTANCE) COMPOSITION	Polymyxin E1-I ≤8 .5%	0.5%
	Polymyxin E3:≤5.5%	3.2%
	Polymyxin E1-7MOA:≤5.0%	3.7%
	Polymyxin E6:≤4.5%	1.0%
	Polymyxin E1-Nva: ≤4.5%	ND
	Polymyxin E4+E1-Va1 ≤3.0%	2.0%
	Polymyxin E2-I ≤2 .5%	0.9%
	Polymyxin2,3-dehydro E1: ≤1.5%	0.4%
	SUM :≥86.0%	93.2%
RELATED SUBSTANCES	IMPURITY B:≤4.0%	ND
	Any impurity:≤2.5%	1.4%
	Not more than 4 such impurities exceed 1.0%	4
	Total impurity : ≤11.0%	6.7%
DRIED SUBSTANCE SULFATE	16.0~18.0%	17.2%
SULFATED ASH	≤1.0%	0.3%
(DRIED BASIS)ASSAY	≥19000IU/mg	23883IU/mg
( MOISTED BASIS) ASSAY		23453IU/mg

Antibiotic drugs, produced by polymyxin bacteria, have strong antibacterial effects on Gram negative bacteria and are used to treat intestinal diseases caused by Gram negative bacteria. Sulfuric colistin is used to penetrate the cell membrane of bacteria and study the anti hemagglutination effect of mannose, as well as the antibiotic resistance of certain chemical books, such as Baumann. It has also been used to study the hepatotoxicity in rat kidneys, MIC values against Pseudomonas aeruginosa, time killing kinetics, and post antibiotic effects (PAE)

Colistin Sulfate is a narrow-spectrum fungicide. It has a strong antibacterial effect on gram-negative bacteria such as Escherichia coli, Salmonella, Pasteurella, Shigella, Brucella, Vibrio, Pseudomonas aeruginosa, among them, it has a strong bactericidal effect on Pseudomonas aeruginosa and Vibrio. The bactericidal mechanism is to damage the bacterial cell membrane, increase its permeability, leak amino acids, purines, pyrimidines, K+, etc., and also affect the function of nucleoplasm and ribosome, leading to bacterial death. bacteria are not easy to develop resistance to this product, and have complete cross resistance with polymyxin B, but no cross resistance with other antibacterial drugs. All gram-positive bacteria and Proteus, Brucella, Serratia are resistant to this product. Sulfuric colistin is mainly used for the treatment of intestinal infections caused by Gram negative bacteria, and for external use in the treatment of Pseudomonas aeruginosa infections caused by burns and trauma. As a feed drug additive, it has a growth promoting effect.

mode of transportation
By Air	By Express	By Sea
suitable for >50	suitable for sampple order or <50	suitable for >300
Fast:3-7 days	Fast:3-10 days	Fast: 7-45 days
lower than the express cost	high shipping cost	lowest cost

Qingdao Qingmei Biotech Co., Ltd is a pharmaceutical company, which is to expand international business and strategic cooperation with Contract Manufacturing on Supplements(Hard Capsules, Softgels, Powders, Sachet), Active Ingredients for Human Health and Animal Health, Herbal Extracts, Food Additives, Feed Additives, Vitamins, Amino Acids, Minerals, Cosmetics raw materials, Pet Medicines, Disinfectant, Farming and Fishery Industry.

The company is located in the beautiful coastal city of Qingdao, near City Hall and the May Fourth Square, and also close to the port, so that it has convenient traffic conditions for trade. The company's business focuses on the development and promotion of the pharmaceutical chemicals, animal health, food additives, plant extracts, cosmetic raw materials, intermediates and other fine chemicals. Production in Qingmei is in accordance with GMP standards, and files are compiled and registered in regulated market to ensure smooth supply channels. Guided by the market development, Qingmei works hard to cover more customers.

Our products are approved by cGMP, CEP/COS, FDA, TGA, EUGMP, FAMI-QS and also Halal, Kosher etc.

Our products are widely sold to regions of Asia, Africa, Europe, Latin America, and long-term stable cooperative relations have been established with merchants from hundreds of countries and regions with our cooperation agencies in Turkey, South Africa, Indonesia, Russia, Brazil, Canada and the United States working stably. We are looking forward to making progress together with you!

1:Can I get some samples before bulk order?
Most products provide free samples, but the shipping cost be paid by customers.

2: What's your MOQ?
For the high value product, our MOQ starts from 10g,100g and 1kg.

3: Which kind of payment terms do you accept?
PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C.

4.How to place an order?
You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and then we will give you a quote. If you choose one of the above payment methods, we will arrange the delivery for you.

5:How about your delivery time?
A: Generally, it will take 5 to 7 days after receiving your advance payment.

6:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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