Factory Supply 2, 3-Dimercaptosuccinic Acid Powder Dmsa

Min.Order: 1

Product origin: Nanjing, Jiangsu, China

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Complaint

US$ 1180 ~ 1500

Description

2,3-Dimercaptosuccinic Acid Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of 2,3-Dimercaptosuccinic Acid is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environm

Basic Information:

Product Name	2,3-Dimercaptosuccinic Acid/Dimercaptosuccinic Acid
Grade	Medicine Grade
Specification	98%
Apperance	White Powder
Test method	HPLC
CAS	304-55-2
MW	182.22
MF	C4H6O4S2

Function :

2,3-Dimercaptosuccinic Acid Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of 2,3-Dimercaptosuccinic Acid is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. Dimercaptosuccinic Acid can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.

Another application for 2,3-Dimercaptosuccinic Acid is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. Dimercaptosuccinic Acid is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a 2,3-Dimercaptosuccinic Acid challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, 2,3-Dimercaptosuccinic Acid share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.

The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (2,3-Dimercaptosuccinic Acid) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound 2,3-Dimercaptosuccinic Acid.

Application :

Dimercaptosuccinic acid is a medication used to treat lead, mercury, and arsenic poisoning.
Dimercaptosuccinic acid is in the chelating agent family of medications. It works by binding with lead and a number of other heavy metals allowing them to leave the body in the urine.

Technical Specification:

Items	Requirements	Results
Appearance:	White crystalline powder	White crystalline powder
Identification
HPLC	The principal spot obtained with test solution corresponds in position, appearance ,and intensity with that obtained from reference solution.	Conforms
Residue on ignition	≤0.5%	0.32%
Loss on drying	≤ 0.3%	0.05%
Melting Pint	190~194°C	192~194°C
PH	2.5~3.0	2.5
Residual on Ignition	≤ 1000ppm	Complies
Iron(Fe)	≤10ppm	<10ppm
Heavy metal Pb : Cadmium(Cd) : As : Hg:	≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm	<10ppm Complies 0.3ppm Complies Negative
DMSO content	≤0.01%	0
Assay	≥98%	99.20%
Conclusion:	The product conforms to USP36.

Shipping & Storage:

Delivery:Sea/Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 38cm (Diameter)*50cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months

Our Service:

1.Free sample
2.Owning cultivation base as 100% Natural material stable source.
3.Manufacturer direct supply, Powerful R&D team and advanced test center
4.ISO/KOSHER/HALAL/FDA Certificate
5.Leading plant extract manufacturer in China.
6.No excuse return of goods
7.OEM & ODM is available

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