99% Pharmaceutical Grade Custom Peptides Ll-37 Raw Powder CAS 154947-66-7 Ll-37 for Anti-Inflammatory

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Product origin: Suzhou, Jiangsu, China
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US$ 1500 ~ 1700

Description
99% Pharmaceutical Grade Custom Peptides Ll-37 Raw Powder CAS 154947-66-7 Ll-37 for Anti-Inflammatory
Product nameLl-37
AppearanceWhite powder
Purity99%
StorageKeep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life24 Months


Description

The cathelicidin anti-microbial peptide LL-37 is involved in the reepithelialization of human skin wounds and is

lacking in chronic ulcer epithelium. LL-37(human) is a cathelicidin-derived peptide with antimicrobial and angiogenic

activity. Antimicrobial peptide derivative of human cathelicidin.

Antimicrobial peptide derivative of human cathelicidin. Induces FPRL1-mediated chemotaxis of human neutrophils,

monocytes and T cells in vitro. Promotes wound healing following skin-targeted electroporation of a plasmid encoding

hCAP-18/LL-37 in mice. Also triggers apoptosis in colon cancer cells. 



Application&Function

LL-37 is the only known human Cathelicidin is a big protein family where the members exhibit diverse functions.

These peptides, essentially produced by macrophages and polymorphonuclear leukocytes (both types of white blood

cells), have bactericidal action. They have been found to have shown other substantial effects as well. The entire group

is often referred to as antimicrobial peptides (AMPs). LL-37 in particular has been found to play significant roles in

autoimmune disease, cancer, and wound healing.


1.Reduce apoptotic death of keratinocytes.

2.Improve IFN-alpha synthesis.

3.Suppress signaling through toll-like receptor 4 (TLR4).

4.Modify chemotaxis of neutrophils and eosinophils.

5.Trigger IL-18 production, and reduce levels of atherosclerotic plaques.


 






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