Description
Ketoprofen
Standard: USP33, BP2009, EP6
CAS No.: 22071-15-4
EC No.: 244-759-8
Molecular Formula: C16H14O3
Molecular Weight: 254.28
Acidity or Alkalinity: PH3-4
Loss on drying: Not more than 0.5%
Assay: >99.6%
Specific Rotation: +1° ~ -1°
Melting Point: 92.0oC- 97.0oC
Residue on ignition: Not more than 0.2%.
Appearance: White crystalline powder, Odourlessness
Solubility: Practically insoluble in water, freely soluble in acetone, in alcohol and in methylene chloride.
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for relief of symptoms of arthritis, fever, as an analgesic (pain reliever), especially where there is an inflammatory component, and dysmenorrhea. Ketoprofen is known to have an antiplatelet effect, though it is relatively mild and short-lived when compared with aspirin or other better-known antiplatelet drugs
Ketoprofen is a medication used for the management and relief of osteoarthritis symptoms. The brand names of this medication are Orudis, Oruvail, and Actron. Osteoarthritis is a type of arthritis that results due to the linings of the joints breaking down. This medication soothes symptoms of the condition, such as stiffness, tenderness, swelling, and pain. Ketoprofen is also used to treat rheumatoid arthritis, which is an arthritis that comes from the joint linings swelling up. There are both non-prescription and prescription versions of the medication
Dexketoprofen
Synonym
(+)-hydratropicaci; (S)-(+)-KETOPROFEN; (S)-KETOPROFEN; (S)-(+)-3-BENZOYL-ALPHA-METHYLBENZENE-ACETIC ACID; [S]-2-[3-BENZOYLPHENYL]PROPIONIC ACID; Dexketoprofen; 3-(1-Hydrocarboxyethyl)benzophenone; Dexktoprofen
CAS No: 22161-81-5
Formula: C16H14O3
Molecular Weight: 254.28
Character: Colorless crystalline solid
Melting point: 69~71º C
Specification: By standard
Quality Standard: CP(2010), USP, BP, EP and Company Standard
Stability: Stable under atmospheric pressure, avoid the oxide.
Usage: Used in the treatment of mild - moderate pain
Storage: Be sealed in a sun-block, ventilated, and dry place
Dexketoprofen is called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action.
Dexketoprofen Trometamol
Synonym: (s)-ketoprofen trometamol; Dexketoprofen trometamol; 2-amino-2-(hydroxymethyl)-1, 3-propanediol (s)-3-benzoyl-alpha-methylbenzeneacetate; L-Ketoprofen trometamol; Dexketoprofen TroMetaMol API
CAS No: 156604-79-4
Formula: C16H14O3. C4H11NO3
Molecular Weight: 375.418
Character: White crystalline solid
Specification: By standard
Quality Standard: CP(2010), USP, BP, EP and Company Standard
Usage: For all the pains, suitable for short term to eliminate trauma, postoperation pain, gall, and tormenting, etc.
characters
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A white or almost white ,crystalline powder
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IR Absorption
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IR spectrum of sample is the same with USP
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CRS spectrum
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UV Absorption
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Absorptivities at the wavelength of maximum absorbance at about 258nm do not differ by more than 3.0% calculated on the dried basis
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Melting Range
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92~97°C
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Specific Rotation
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Between +1°and –1°
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Loss on Drying
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0.5% max
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Residue on Ignition
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0.2% Max
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Heavy Metals
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0.002% Max
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Any Individual Impurity
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0.2% max
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Total Impurities
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1.0% max
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Organic volatile impurities
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Meet the requirements
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Assay
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98.5~101.0
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Complaint
