Tianeptine Sodium
CAS Number: 30123-17-2
Molecular formula: C21H24ClN2NaO4S
Molecular weight: 458.93
EINECS number: 250-059-3
Tianeptine sodium salt is a tricyclic antidepressant. Its antidepressant mechanism is different from traditional tricyclic antidepressants. It can increase the reuptake of 5-HT in the synaptic space and may increase 5-HT nerves. The effect of meta-conduction. No affinity for choline or adrenali ne receptors. The antidepressant effect is similar to tricyclics, but the tolerability is better than tricyclics. In animal experiments, it can increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate the recovery of their functions after being inhibited; it can increase the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus. Tianeptin sodium is absorbed quickly and completely in the digestive tract. The distribution is rapid, and the PPB is as high as 94%.