Fluoroquinolonic acid Product Name Fluoroquinolonic acid CAS 86393-33-1
MF C13H9ClFNO3
MW 281.67
EINECS 405-050-0
MOL File 86393-33-1.mol
Chemical Properties
Melting point 242-245 °C(lit.) Boiling point 467.3±45.0 °C(Predicted) Density 1.652±0.06 g/cm3(Predicted) storage temp. Sealed in dry,Room Temperature pka 6.36±0.41(Predicted) form neat InChIKey ISPVACVJFUIDPD-UHFFFAOYSA-N CAS DataBase Reference 86393-33-1(CAS DataBase Reference)
Usage And Synthesis Chemical Properties
Off-White Crystalline Powder
Uses
An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial
Uses
A metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.
Uses
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.
General Description
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.
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