Complaint
| Product Name | linagliptin |
| CAS | CAS 668270-12-0 |
| Grade | Phamaceutical Grade |
| Color | White to light yellow powder |
| Purity | 99% |
| Shelf life | 2 years |
| items | Specifications | Results |
| Appearance | White or off-white crystalline powder | Conforms |
| HPLC | The retention time of the major peaking the chromatogram of the sample corresponds to that exhibited by the working standard | Conforms |
| Loss on drying | No more than 1.0% | 0.40% |
| Residue on Ignition | No more than 0.1% | 0.02% |
| Heavy Metals | No more than 20ppm | <10ppm |
| Related substances | Total impurities no more than 1.0% | 0.50% |
| Single impurity no more than 0.5% | Conforms | |
| Residual solvents | EthyI acetate No more than 0.1% | Conforms |
| Ethanol No more than 0.1% | Conforms | |
| Purity | No less than 99.0% | 99.50% |
Application
Linagliptin is a kind of dipeptide peptidase 4 (DPP - 4) inhibitors used as dietary and exercise in type 2 diabetes in adult auxiliary treatment to improve blood sugar control.
Linagliptin is used with a proper diet and exercise program and possibly with othermedications to control high blood sugar. It is used by people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
99% CAS 668270-12-0 Linagliptin Ondero for Type 2 Diabetes
Functions
1. Incretin (Incretin) has the role of intestinal promoting insuli n B cells to secrete insuli n, mainly including glucose-dependent insuli notropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). DDP-4 is a serine protease located on the cell surface, which is widely found in plasma and in vivo tissues (such as kidney, liver, small intestine villi, endothelial cells, etc.). Rilalitine is a selective DPP-4 inhibitor that inhibits the activity of the enzyme by reversibly binding to DPP-4, delays GLP-1 degradation, enhances GLP-1 activity, and stimulates glucose-dependent Insuli n secretion, and reduce circulating levels of glucagon, thereby regulating blood glucose levels in patients with type 2 diabetes.
2. Compared with other DPP-4 inhibitors, the main advantages of liradetine is: with excellent renal safety, and can effectively reduce glycosylated hemoglobin. Lilardine mainly in the form of excretion of fecal excretion, the oral administration, the amount of renal excretion is only 5% of the dose, even if the intravenous administration, and only 30.8% of the excretion by the kidney, so the patient did not need treatment Regularly check the liver, kidney function and dose adjustment, all patients can be a unified fixed dose, easy to prescribe.
Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales.
Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world.
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.
