Pahrmaceutical Intermmedia Linagliptin Treat Type II Diabetes CAS 668270-12-0

Min.Order: 50
Product origin: Jinan, Shandong, China
Infringement complaint: complaintComplaint
US$ 4 ~ 8

Description
Product Description
Product Namelinagliptin 
CASCAS 668270-12-0
GradePhamaceutical Grade
ColorWhite to light yellow powder
Purity99%
Shelf life2 years

Linagliptin, also known as BI-1356, is a DPP-4 inhibitor developed by Boehringer Ingelheim for treatment of type II diabetes. Linagliptin (once-daily) was approved by the US FDA on 2 May 2011 for treatment of type II diabetes. It is being marketed by Boehringer Ingelheim and Lilly.
Detailed Photos
 
itemsSpecificationsResults
Appearance

White or off-white crystalline

powder

Conforms
HPLC

The retention time of the major peaking

the chromatogram of the sample corresponds

to that exhibited by the working standard

Conforms
Loss on dryingNo more than 1.0%0.40%
Residue on IgnitionNo more than 0.1%0.02%
Heavy MetalsNo more than 20ppm<10ppm
Related substancesTotal impurities no more than 1.0%0.50%
 Single impurity no more than 0.5%Conforms
Residual solventsEthyI acetate No more than 0.1%Conforms
 Ethanol No more than 0.1%Conforms
PurityNo less than 99.0%99.50%
Function and Application

Application
 
Linagliptin  is a kind of dipeptide peptidase 4 (DPP - 4) inhibitors used as dietary and exercise in type 2 diabetes in adult auxiliary treatment to improve blood sugar control.

Linagliptin is used with a proper diet and exercise program and possibly with othermedications to control high blood sugar. It is used by people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

99% CAS 668270-12-0 Linagliptin Ondero for Type 2 Diabetes


Functions
 1. Incretin (Incretin) has the role of intestinal promoting insuli n B cells to secrete insuli n, mainly including glucose-dependent insuli notropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). DDP-4 is a serine protease located on the cell surface, which is widely found in plasma and in vivo tissues (such as kidney, liver, small intestine villi, endothelial cells, etc.). Rilalitine is a selective DPP-4 inhibitor that inhibits the activity of the enzyme by reversibly binding to DPP-4, delays GLP-1 degradation, enhances GLP-1 activity, and stimulates glucose-dependent Insuli n secretion, and reduce circulating levels of glucagon, thereby regulating blood glucose levels in patients with type 2 diabetes.

2. Compared with other DPP-4 inhibitors, the main advantages of liradetine is: with excellent renal safety, and can effectively reduce glycosylated hemoglobin. Lilardine mainly in the form of excretion of fecal excretion, the oral administration, the amount of renal excretion is only 5% of the dose, even if the intravenous administration, and only 30.8% of the excretion by the kidney, so the patient did not need treatment Regularly check the liver, kidney function and dose adjustment, all patients can be a unified fixed dose, easy to prescribe.

Packaging & Shipping

Company Profile

Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales. 

Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world. 

FAQ

1.Can I get some samples?
Yes, usually a 10-20g sample.

2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.

3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.

4. How to deliver the goods?
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

5. What is the shelf life for the products?
Most products shelf life 24-36 months. 

6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.

7. How about the validity of the offer? 
Usually, our offer is valid for 1 week. However, validity might vary between different products.

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