Complaint
| Generic Name | Azithromycin Capsules 250mg |
| Strength | 250mg |
| Packing | 6capsules/box |
| Origin | China |
1. Acute pharyngitis and acute tonsillitis caused by Streptococcus pyogenes.
2. Acute attacks of sinusitis, otitis media, acute bronchitis and chronic bronchitis caused by sensitive bacteria.
3. Pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae and Mycoplasma pneumoniae.
4. Urethritis and cervicitis caused by Chlamydia trachomatis and non-multidrug-resistant Neisseria gonorrhoeae.
5. Skin and soft tissue infections caused by sensitive bacteria.
Usage and dosage:
Take orally, one hour before or two hours after meals.
Adult dosage:
1. For sexually transmitted diseases caused by Chlamydia trachomatis or sensitive Neisseria gonorrhoeae, only 1. Og (4 capsules) should be taken orally once.
2. Treatment of other infections: 0.5 g (2 capsules) on the 1st day, 0.25 g (1 capsule) on the 2nd to 5th day; Or 0.5g (2 capsules) a day for 3 days.
Dosage for children:
1. For the treatment of otitis media and pneumonia, on the first day, take 10mg/kg daily according to body weight (maximum amount per day is not more than 0.5g (2 capsules)), and on the 2nd to 5th day, take 5mg/kg daily according to body weight (maximum amount per day is not more than 0.25g (1 capsule)).
2, the treatment of children's pharyngitis, tonsillitis, a day according to the weight of 12mg/kg (the maximum amount of a day is not more than 0.5g (2 capsules)), for 5 days.
1. Eating can affect the absorption of azithromycin, so it should be taken orally 1 hour before or 2 hours after meals.
2. Patients with mild renal insufficiency (creatinine clearance > 40ml/ min) does not require dose adjustment, but there is no data on the use of azithromycin in patients with more severe renal insufficiency, and azithromycin should be administered with caution in these patients.
3. Because the hepatobiliary system is the main way of azithromycin excretion, it should be used with caution in patients with liver insufficiency and should not be used in patients with severe liver disease. Liver function was followed up regularly during medication.
4. If allergic reactions occur during medication (such as angioneurotic edema, skin reactions, Stevens-Johnson syndrome, toxic epidermal necrosis, etc.), the medication should be stopped immediately and appropriate measures should be taken. Some reactions caused by azithromycin may recur and require longer-term observation and treatment.
5. As with other antibiotics, attention should be paid to symptoms of double infection caused by non-sensitive bacteria, including fungi.
6. Pseudomembranous enteritis should be considered if the patient develops symptoms of diarrhea during treatment. If the diagnosis is confirmed, appropriate treatment measures should be taken, including water and electrolyte balance and protein supplementation.
Medication for special population:
There are currently no fully controlled clinical trials in pregnant women. Since the results of animal reproductive studies do not always predict the condition in humans, the benefits and risks of use in pregnant women must be carefully weighed.
Drug interaction:
1. It should not be taken with antacids containing aluminum or magnesium, which can reduce the peak concentration of the drug in blood; If it must be used together, it should be given 1 hour before or 2 hours after taking the above medication.
2. The concentration of theophylline in plasma can be increased when combined with theophylline. Attention should be paid to the detection of plasma theophylline level.
3. Prothrombin time should be checked when combined with warfarin.
