99% Ep Powder 117976-90-6 Rebeprazole Sodium

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Product origin: Wuhan, Hubei, China

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US$ 95 ~ 150

Description

99% EP powder 117976-90-6 Rebeprazole sodium

Product Name: Rebeprazole sodium
CAS: 117976-90-6
MF: C18H20N3NaO3S
MW: 381.42
EINECS: 222-630-7
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Rabeprazole
Chemical Properties White Crystalline Solid
Usage anthelminthic, antiseptic, expectorant

Rabeprazole is a white to yellowish white powder, odorless, and its molecular weight is 381.43. This product is easily soluble in water or meth anol, soluble in absolute etha nol or eth yl ace tate, and almost insoluble in et her or et hane. This product does not show optical rotation, but has a thermo-absorption property. Its melting point is 225°C, and its distribution coefficient in a water/octane system with a pH of 7.0 is about 214.

Rabeprazole and omeprazole are both proton pump inhibitors. The so-called proton pump, or H+/K+-ATPase, is the last step of gastric acid secretion. Proton pump inhibitors can efficiently and quickly inhibit the proton pump and reduce gastric acid secretion. It is currently the most advanced class of drugs for the treatment of gastrointestinal diseases such as gastric and duodenal ulcers, reflux esophagitis, and gastric Helicobacter pylori infection. Compared with other types of acid inhibitors, proton pump inhibitors have strong acid inhibitory effects, high specificity, and long duration.

Package	carton drum with two plastic bags inside
Net weight	25KG/Drum
Storage	Sealed in cool and dry place to avoid moisture and light
Shelf life	2 years when properly stored
Lead time	1~3 days after confirmation

Test Items	Test Standard
Appearance	White or slightly yellowish-white hygroscopic powder
Solubility	Very soluble to freely soluble in water,very soluble in anhydrous ethanol, practically insoluble in h eptane
Identification	Infrared absorption spectrum is identical to that of rebeprazole sodium reference standard.
	Loss on drying (see tests below)
	It gives reaction (a) of sodium
PH	9.5~11.5
Loss on drying	≤0.5%
Related substances (HPLC)	Impurity A ≤0.8%
	Unspecified impurities≤0.1%
	Total impurities ≤1.0%
Residual solvents (GC)	Meth ylene Chloride ≤600ppm
	Eth anol ≤5000ppm
	Isop ropyl ether≤5000ppm
	Ace tone≤5000ppm
Assay	97.0%~102.0% (C18H20N3NaO3S, on dried basis)
Microbial limit	Aerobe count ≤1000CFU/g
	Mold and yeasts count≤100CFU/g
	E.coli: absent for per gram