Product Name: | Bicalutamide |
Synonyms: | (+-)--2-hydroxy-2-methyl;propanamide,n-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl);Bicalutamide (Subject to patent free);ICI-176334;CASODEX;BICALUTAMIDE;N-[(4-CYANO-3-TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPANAMIDE;N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPIONANILIDE |
CAS: | 90357-06-5 |
MF: | C18H14F4N2O4S |
MW: | 430.37 |
EINECS: | 200-001-8 |
Bicalutamide was launched in the United Kingdom, its first worldwide market, for the treatment of advanced prostate cancer in combination with an LHRH analog or surgical castration. A non-steroidal, peripherally selective antiandrogen, bicalutamide inhibits the action of at target sites by competitive binding to the cytosolic androgen receptor. It was reportedly well tolerated with no significant cardiovascular and metabolic side effects due to the benefit of lacking any steroid activity. The efficacy of bicalutamide as a monotherapy has been demonstrated clinically. Promising response rates were also reported in treating colorectal, breast, pancreas and non-small cell lung cancers.
Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal)
Bicalutamide (CDX) has been used as an androgen receptor (AR) antagonist in prostate, bladder cancer cell lines and human fetal skeletal muscle cells. It has also been used as a supplement in RPMI 1640 for culturing androgen-independent LNCaP (LNCaP-AI) cell line.
Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.0% |
β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 99.0% |
Olivetol(3,5-hydroxypentylbenzene) | 500-66-3 | 99.0% |
Compound 7P | 1890208-58-8 | 98.0% |
Noopept,GVS-111 | 157115-85-0 | 99.5% |
Piracetam | 7491-74-9 | 99.0% |
Aniracetam | 72432-10-1 | 99.0% |
Nefiracetam | 77191-36-7 | 99.0% |
Pramiracetam | 68497-62-1 | 99.0% |
Fasoracetam | 110958-19-5 | 99.0% |
Sunifiram | 314728-85-3 | 99.5% |
Coluracetam | 135463-81-9 | 99.0% |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99.0% |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50.0% |
Citicoline | 987-78-0 | 99.0% |
Galantamine Hydrobromide | 69353-21-5 | 98.0% |
PRL-8-53 | 51352-87-5 | 99.0% |
NSI-189 Phosphate | 1270138-41-4 | 99.0% |
NSI-189 | 1270138-40-3 | 99.0% |
Tianeptine | 66981-73-5 | 99.0% |
Tianeptine sodium | 30123-17-2 | 99.0% |
Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
Agomelatine | 138112-76-2 | 99.0% |
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Suitable Quantity | Under 25KG | Under 100KG | More Than 100KG |
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