Pharmaceutical Chemical Products Monobenzone CAS 103-16-2

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Product origin: Xi'an, Shaanxi, China
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US$ 130 ~ 180

Description
Product NameMonobenzone
Specs99%
CAS103-16-2
MFC13H12O2
CertificateISO
Shelf Life2 Years

Monobenzone, is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. It is a colourless solid that is classified as the monobenzyl ether. Monobenzone is soluble in alcohol, benzene, and practically insoluble in water.

The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.

The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes. Therefore, monobenzone is used as a topical medicine to permanently depigment normal skin surrounding vitiliginous lesions only in patients with disseminated (greater than 50 percent of body surface
area) idiopathic vitiligo. Monobenzone is also being considered for the treatment of Melanoma.

Monobenzone is also used to derive dyes for fiber dyeing and is used in the rubber industry.
1.Monobenzone Powder is a compound used as a topical drug for medical depigmentation.
2.The topical application of monobenzone powder in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
3.Monobenzone Powder may cause destruction of melanocytes and permanent depigmentation.
4.The histology of the skin after depigmentation with topical monobenzone powder is the same as that seen in vitiligo.
5.The epidermis is normal except for the absence of identifiable melanocytes.

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