Supply High quality/High cost performance Antineoplastic Agents CAS 33419-42-0 Etoposide

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Product origin: Guangzhou, Guangdong, China

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US$ 0.2 ~ 0.5

Description

Product name	Etoposide
CAS	33419-42-0
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Etoposide
CAS:33419-42-0
MF:C29H32O13
MW:588.56
EINECS:251-509-1
Mol File:33419-42-0.mol
Melting point:236-251 °C(lit.)
alpha D20 -110.5° (c = 0.6 in chloroforim)
Boiling point:563.9°C (rough estimate)
Density 1.2966 (rough estimate)
refractive index -110.5 ° (C=0.6, CHCl3)
storage temp. Store at RT
solubility DMSO: 30 mg/mL
pka9.8(at 25ºC)
form powder
color white
Water Solubility Insoluble in water.

Description
An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor
UsesA DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.
Usesanticonvulsant
IndicationsEtoposide (VePesid) is a semisynthetic derivative of podophyllotoxin that is produced in the roots of the American mandrake, or May apple. Unlike podophyllotoxin and vinca alkaloids, etoposide does not bind to microtubules. It forms a complex with the enzyme topoisomerase II, which results in a single-strand breakage of DNA. It is most lethal to cells in the S- and G2-phases of the cell cycle. Drug resistance to etoposide is thought to be caused by decreased cellular drug accumulation.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company phi
osophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
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high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

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